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Cat. No.: HY-155411

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HPSE1-IN-2

HPSE1-IN-2 (compound 2) is a Heparanase-1 (HPSE1) inhibitor that also inhibits exo-β-d-glucuronidase (GUSβ) and glucocerebrosidase (GBA) activity.

For research use only. We do not sell to patients.

CAS No.: 2876926-27-9
Formula: C₂₃H₂₄N₂O₆
Molecular Weight:424.45

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

HPSE1-IN-2 Chemical Structure

CAS No.: 2876926-27-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

HPSE1-IN-2 (compound 2) is a Heparanase-1 (HPSE1) inhibitor that also inhibits exo-β-d-glucuronidase (GUSβ) and glucocerebrosidase (GBA) activity^[1].

IC₅₀ & Target

Heparanase-1 (HPSE1), exo-β-d-glucuronidase (GUSβ) and glucocerebrosidase (GBA)^[1]

All Endogenous Metabolite Isoforms :

Chemical Information

CAS No. 2876926-27-9
Molecular Weight 424.45
Formula C₂₃H₂₄N₂O₆
SMILES

CO[C@H]1[C@@H]([C@H](C2=NC(CCC3=CC(OC4=CC=CC=C4)=CC=C3)=CN2[C@@H]1C(O)=O)O)O
Structure Classification
- Others
Initial Source
- Endogenous metabolite
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Imai Y et al. Discovery of a novel tetrahydroimidazo [1, 2-a] pyridine-5-carboxylic acid derivative as a potent and selective heparanase-1 inhibitor utilizing an improved synthetic approach[J]. Bioorganic & Medicinal Chemistry Letters, 2023: 129543.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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HPSE1-IN-2

All Endogenous Metabolite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

HPSE1-IN-2 Related Classifications

HY-155411 Related Classifications