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Cat. No.: HY-123799

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SB-699393

B-699393 (Compound 17) is a BRAF inhibitor (K_d = 7.2 nM) that can cross the blood-brain barrier. SB-699393 can be used for research on stroke.

For research use only. We do not sell to patients.

CAS No.: 502638-39-3
Formula: C₂₃H₂₃N₃O₃
Molecular Weight:389.45

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

SB-699393 Chemical Structure

CAS No.: 502638-39-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

B-699393 (Compound 17) is a BRAF inhibitor (K_d = 7.2 nM) that can cross the blood-brain barrier. SB-699393 can be used for research on stroke^[1].

All Raf Isoforms :

Chemical Information

CAS No. 502638-39-3
Molecular Weight 389.45
Formula C₂₃H₂₃N₃O₃
SMILES

O/N=C1C2=CC=C(C3=C(C4=CC=NC=C4)OC(CN5CCOCC5)=C3)C=C2CC/1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Takle AK, et al. The identification of potent, selective and CNS penetrant furan-based inhibitors of B-Raf kinase. Bioorg Med Chem Lett. 2008 Aug 1;18(15):4373-6. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
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References

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SB-699393

All Raf Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

SB-699393 Related Classifications

HY-123799 Related Classifications