A 1120 (Standard)
A 1120 (Standard) is the analytical standard of A 1120 (HY-107633). This product is intended for research and analytical applications. A 1120 is a high-affinity nonretinoid retinol-binding protein 4 (RBP4) antagonist with a Ki value of 8.3 nM. A 1120 disrupts the interaction between RBP4 and its binding partner transthyretin.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- CAS No.: 1152782-19-8
- 화학식: C20H19F3N2O3
- 분자량:392.37
-
보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- 순도&문서
- References
-
Help & FAQs
Biological Activity
Ki: 8.3 nM (Retinol-binding protein 4)[1]
Chemical Information
-
CAS No. 1152782-19-8
-
분자량 392.37
-
화학식 C20H19F3N2O3
-
SMILES
FC(F)(C1=C(C2CCN(C(NC3=C(C=CC=C3)C(O)=O)=O)CC2)C=CC=C1)F
-
선적
Room temperature in continental US; may vary elsewhere.
-
보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Motani A, et al. Identification and characterization of a non-retinoid ligand for retinol-binding protein 4 which lowers serum retinol-binding protein 4 levels in vivo. J Biol Chem. 2009 Mar 20;284(12):7673-80. [Content Brief]
[2]. Dobri N, et al. A1120, a nonretinoid RBP4 antagonist, inhibits formation of cytotoxic bisretinoids in the animal model of enhanced retinal lipofuscinogenesis. Invest Ophthalmol Vis Sci. 2013 Jan 7;54(1):85-95. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
A 1120 (Standard) Related Classifications
HY-107633R Related Classifications
Powered by Bioz