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A 1120 

Cat. No.: HY-107633 Purity: >99.0%
Handling Instructions

A 1120, a nonretinoid retinol-binding protein 4 (RBP4) antagonist, has a high affinity with the Ki value of 8.3 nM, which disrupts the interaction between RBP4 and its binding partner transthyretin.

For research use only. We do not sell to patients.

A 1120 Chemical Structure

A 1120 Chemical Structure

CAS No. : 1152782-19-8

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 264 In-stock
Estimated Time of Arrival: December 31
5 mg USD 240 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

A 1120, a nonretinoid retinol-binding protein 4 (RBP4) antagonist, has a high affinity with the Ki value of 8.3 nM, which disrupts the interaction between RBP4 and its binding partner transthyretin[1][2].

IC50 & Target

Ki: 8.3 nM (Retinol-binding protein 4)[1]

In Vitro

The IC50 of A 1120 is 90 nM on human RBP4 and 66 nM on mouse RBP4[1].

Molecular Weight

392.37

Formula

C₂₀H₁₉F₃N₂O₃

CAS No.

1152782-19-8

SMILES

FC(F)(C1=C(C2CCN(C(NC3=C(C=CC=C3)C(O)=O)=O)CC2)C=CC=C1)F

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
References

Purity: >99.0%

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A 1120
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HY-107633
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