Delphinidin 3-rutinoside chloride
Based on 1 publication(s) in Google Scholar
Delphinidin 3-rutinoside chloride is an anthocyanin component. Delphinidin 3-rutinoside chloride is isolable from the fruits of blackcurrant Ribes nigrum L. Delphinidin 3-rutinoside chloride activates the ETB receptor and stimulates the NO/cGMP pathway. Delphinidin 3-rutinoside chloride increases cyclic guanosine monophosphate production and reduces the phosphorylation level of Myosin regulatory light chain. Delphinidin 3-rutinoside chloride stimulates GLP-1 secretion. It significantly induces relaxation of bovine ciliary muscle strips contracted by ET-1 and inhibits ET-1-induced contraction of bovine ciliary muscle strips. Delphinidin 3-rutinoside chloride is applicable to research related to type 2 diabetes.
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- Purity: 98.83%
- CAS No.: 15674-58-5
- 화학식: C27H31ClO16
- 분자량:646.98
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보관:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Delphinidin 3-rutinoside chloride
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Biological Activity
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ETB |
Delphinidin 3-rutinoside (3×10-5 M) chloride significantly induces relaxation of bovine ciliary muscle strips pre-contracted by ET-1[1].
Delphinidin 3-rutinoside (1×10-4 M) chloride inhibits ET-1-induced contraction of bovine ciliary muscle strips via an ETB receptor/NO/guanylate cyclase-dependent pathway, but exerts no effect on carbachol-induced contraction[1].
Delphinidin 3-rutinoside (100 μM; 2 h) chloride significantly increases GLP-1 secretion in mouse GLUTag enteroendocrine L cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 15674-58-5
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Appearance Solid
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분자량 646.98
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화학식 C27H31ClO16
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Color Brown to reddish brown
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SMILES
OC1=CC(O)=CC2=C1C=C(C(C3=CC(O)=C(C(O)=C3)O)=[O+]2)O[C@@H]4O[C@@H]([C@H]([C@@H]([C@H]4O)O)O)CO[C@H]5[C@@H]([C@@H]([C@H]([C@@H](O5)C)O)O)O.[Cl-]
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Synonyms
Delphinidin 3-O-rutinoside chloride
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Food Chem
Flavonoid-mediated metabolic underpinning quality variation in red bud-sport pear mutants. [Abstract]2025 May 31:489:144992. PMID: 40466530
용액&용해도
DMSO : 50 mg/mL (77.28 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 25 mg/mL (38.64 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
순도&문서
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Data Sheet (284 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Matsumoto H, et al. Delphinidin-3-rutinoside relaxes the bovine ciliary smooth muscle through activation of ETB receptor and NO/cGMP pathway. Exp Eye Res. 2005;80(3):313-322. [Content Brief]
[2]. Tani T, et al. Delphinidin 3-rutinoside-rich blackcurrant extract ameliorates glucose tolerance by increasing the release of glucagon-like peptide-1 secretion. Food Sci Nutr. 2017;5(4):929-933. Published 2017 Apr 7. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 1.5456 mL | 7.7282 mL | 15.4564 mL | 38.6411 mL |
| 5 mM | 0.3091 mL | 1.5456 mL | 3.0913 mL | 7.7282 mL | |
| 10 mM | 0.1546 mL | 0.7728 mL | 1.5456 mL | 3.8641 mL | |
| 15 mM | 0.1030 mL | 0.5152 mL | 1.0304 mL | 2.5761 mL | |
| 20 mM | 0.0773 mL | 0.3864 mL | 0.7728 mL | 1.9321 mL | |
| 25 mM | 0.0618 mL | 0.3091 mL | 0.6183 mL | 1.5456 mL | |
| 30 mM | 0.0515 mL | 0.2576 mL | 0.5152 mL | 1.2880 mL | |
| DMSO | 40 mM | 0.0386 mL | 0.1932 mL | 0.3864 mL | 0.9660 mL |
| 50 mM | 0.0309 mL | 0.1546 mL | 0.3091 mL | 0.7728 mL | |
| 60 mM | 0.0258 mL | 0.1288 mL | 0.2576 mL | 0.6440 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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