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Cat. No.: HY-N0918R

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Desmethoxyyangonin (Standard)

(Synonyms: Demethoxyyangonin (Standard); 5,6-Dehydrokavain (Standard))

Desmethoxyyangonin (Standard) is one of the six major kavalactones found in the Piper methysticum (kava) plant. Desmethoxyyangonin (Standard) is a selective inhibitor of monoamine oxidase-B (MAO-B) (IC₅₀: 0.123 µM). Desmethoxyyangonin (Standard) exerts anti-inflammatory effects by inhibiting Jak2/STAT3 and IKK signaling pathways. Desmethoxyyangonin (Standard) induces CYP3A23 expression and leads to skeletal muscle relaxation.

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CAS No.: 15345-89-8
화학식: C₁₄H₁₂O₃
분자량:228.24

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Desmethoxyyangonin (Standard) Chemical Structure

CAS No.: 15345-89-8

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Product Information

Information

신청

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 15345-89-8
분자량 228.24
화학식 C₁₄H₁₂O₃
SMILES

O=C1C=C(OC)C=C(/C=C/C2=CC=CC=C2)O1
Synonyms

Demethoxyyangonin (Standard); 5,6-Dehydrokavain (Standard)
Structure Classification
- Phenylpropanoids
- Other Phenylpropanoids
Initial Source
- Plants
- other families
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Chaurasiya ND, et al. Interactions of Desmethoxyyangonin, a Secondary Metabolite from Renealmia alpinia, with Human Monoamine Oxidase-A and Oxidase-B. Evid Based Complement Alternat Med. 2017;2017:4018724. [Content Brief]

[2]. Chou TW, et al. A plant kavalactone desmethoxyyangonin prevents inflammation and fulminant hepatitis in mice. PLoS One. 2013 Oct 15;8(10):e77626. [Content Brief]

[3]. Baum SS, et al. Effect of kava extract and individual kavapyrones on neurotransmitter levels in the nucleus accumbens of rats. Prog Neuropsychopharmacol Biol Psychiatry. 1998 Oct;22(7):1105-20. [Content Brief]

[4]. Ma Y,et al. Desmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with marked activity on the induction of CYP3A23. Drug Metab Dispos. 2004 Nov;32(11):1317-24. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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