Dspp - dentin sialophosphoprotein Gene

Also Known as Dsp; RDSP2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25254

Summary

Enables Collagen binding activity. Involved in several processes, including animal organ development; cellular response to dexamethasone stimulus; and odontoblast differentiation. Acts upstream of or within positive regulation of calcium ion import. Located in several cellular components, including collagen-containing extracellular matrix; nucleus; and plasma membrane. Biomarker of osteoporosis. Human ortholog(s) of this gene implicated in dentinogenesis imperfecta. Orthologous to human DSPP (dentin sialophosphoprotein). [provided by Alliance of Genome Resources, Apr 2022]

Dspp Products (1)

mRNA Protein Name
NM_012790.3 NP_036922.3 dentin sialophosphoprotein precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables collagen binding IDA
IDA: Inferred from direct assay
22615197 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
23525114 RGD
Biological Process GO Annotation Evidence References Source
involved in biomineral tissue development IEP
IEP: Inferred from expression pattern
20425127 RGD
involved in cartilage development IEP
IEP: Inferred from expression pattern
20679519 RGD
involved in cell differentiation IEP
IEP: Inferred from expression pattern
15308669 RGD
involved in cellular response to dexamethasone stimulus IEP
IEP: Inferred from expression pattern
20666749 RGD
involved in cellular response to hormone stimulus IEP
IEP: Inferred from expression pattern
22946647 RGD
involved in dentinogenesis IEP
IEP: Inferred from expression pattern
24502800 RGD
involved in hair follicle maturation IEP
IEP: Inferred from expression pattern
21908176 RGD
involved in mandibular condyle articular cartilage development IEP
IEP: Inferred from expression pattern
20097540 RGD
involved in odontoblast differentiation IEP
IEP: Inferred from expression pattern
15763925 RGD
involved in odontogenesis of dentin-containing tooth IEP
IEP: Inferred from expression pattern
15533758 RGD
acts upstream of or within positive regulation of calcium ion import IDA
IDA: Inferred from direct assay
23525114 RGD
involved in regulation of odontoblast differentiation IDA
IDA: Inferred from direct assay
15308669 RGD
involved in response to carbohydrate IEP
IEP: Inferred from expression pattern
20088703 RGD
involved in response to hypoxia IEP
IEP: Inferred from expression pattern
24661255 RGD
involved in response to mechanical stimulus IEP
IEP: Inferred from expression pattern
22342686 RGD
involved in response to transforming growth factor beta IEP
IEP: Inferred from expression pattern
22012415 RGD
Cellular Component GO Annotation Evidence References Source
located in collagen-containing extracellular matrix IDA
IDA: Inferred from direct assay
16776771 RGD
located in nucleus IDA
IDA: Inferred from direct assay
23525114 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
23525114 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

dentin sialophosphoprotein

  • Dentin sialoprotein

  • Dentine sialoprotein

  • dentin sailophosphoprotein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-P3386A Selcopintide acetate 99.63% Unkown
HY-P3386 Selcopintide / Unkown
HY-RS04027 DSPP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-Y0332L Potassium dihydrogen phosphate, meets analytical specification of Ph. Eur., NF, E340 Activator / Unkown
HY-RS21329 Dspp Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27848 Dspp Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dspp NCBI NCBI:1834