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  3. Selcopintide acetate

Selcopintide acetate  (Synonyms: Cpne7-DP acetate)

Cat. No.: HY-P3386A Purity: 99.83%
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Selcopintide (Cpne7-DP) acetate consists of a synthetic peptide corresponding to the 10 amino acid residue 344-353 fragment of the hCPNE7 protein. Selcopintide acetate highly reproduces the in vitro effects of CPNE7 by upregulating odontoblast marker genes, DSPP, and Nestin. Selcopintide acetate promotes dentin regeneration in dentinal defects of various degrees and that the regenerated hard tissue demonstrates the characteristics of true dentin.

For research use only. We do not sell to patients.

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Selcopintide acetate Chemical Structure

Selcopintide acetate Chemical Structure

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1 mg USD 50 In-stock
5 mg USD 150 In-stock
10 mg USD 240 In-stock
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Based on 1 publication(s) in Google Scholar

Other Forms of Selcopintide acetate:

Selcopintide acetate Related Antibodies

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Description

Selcopintide (Cpne7-DP) acetate consists of a synthetic peptide corresponding to the 10 amino acid residue 344-353 fragment of the hCPNE7 protein. Selcopintide acetate highly reproduces the in vitro effects of CPNE7 by upregulating odontoblast marker genes, DSPP, and Nestin. Selcopintide acetate promotes dentin regeneration in dentinal defects of various degrees and that the regenerated hard tissue demonstrates the characteristics of true dentin[1].

In Vitro

Selcopintide (Cpne7-DP) acetate directly penetrates odontoblastic cell (MDPC-23 cells) [1].
Selcopintide (1, 10 μg) acetate increases dspp promoter activity in a dose-dependent manner[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Selcopintide acetate Related Antibodies
In Vivo

Selcopintide (Cpne7-DP; human DPCs with 10 µg subcutaneous transplantation in a 0.5% fibrin gel) acetate promotes dentin-like tissue formation and the regeneration of tubular dentin and dentinal tubule occlusion in shallow and deep cavity models[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Immunocompromised mice (NIH-bg-nu-xid)[1]
Dosage: 10 µg
Administration: Subcutaneous transplantation in a 0.5% fibrin gel
Result: Promotes dentin-like tissue formation.
Promotes the regeneration of tubular dentin and dentinal tubule occlusion in shallow and deep cavity models.
Molecular Weight

1444.68

Formula

C64H109N21O17
Appearance

Solid

Color

White to off-white

Sequence

Lys-Tyr-Lys-Gln-Lys-Arg-Arg-Ser-Tyr-Lys
Sequence Shortening

KYKQKRRSYK
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Stored under nitrogen, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (69.22 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.6922 mL 3.4610 mL 6.9219 mL
5 mM 0.1384 mL 0.6922 mL 1.3844 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 0.6922 mL 3.4610 mL 6.9219 mL 17.3049 mL
5 mM 0.1384 mL 0.6922 mL 1.3844 mL 3.4610 mL
10 mM 0.0692 mL 0.3461 mL 0.6922 mL 1.7305 mL
15 mM 0.0461 mL 0.2307 mL 0.4615 mL 1.1537 mL
20 mM 0.0346 mL 0.1730 mL 0.3461 mL 0.8652 mL
25 mM 0.0277 mL 0.1384 mL 0.2769 mL 0.6922 mL
30 mM 0.0231 mL 0.1154 mL 0.2307 mL 0.5768 mL
40 mM 0.0173 mL 0.0865 mL 0.1730 mL 0.4326 mL
50 mM 0.0138 mL 0.0692 mL 0.1384 mL 0.3461 mL
60 mM 0.0115 mL 0.0577 mL 0.1154 mL 0.2884 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SelcopintideCpne7-DPOthersodontoblastic cellCPNE7-derived peptidetubular orthodentinperitubular dentin formationInhibitorinhibitorinhibit

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