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Cat. No.: HY-184026

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MAO-B-IN-58

MAO-B-IN-58 (Compound 2e) is a reversible, selective MAO-B inhibitor with an IC₅₀ of 170 nM against rat MAO-B. MAO-B-IN-58 is applicable for the research of Parkinson's disease and Alzheimer's disease.

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CAS No.: 898540-68-6
화학식: C₁₉H₁₄N₂O₂
분자량:302.33

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

MAO-B-IN-58 Chemical Structure

CAS No.: 898540-68-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
Chemical Information
순도&문서
References
Calculators
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Bioz

Biological Activity

제품 설명

IC₅₀ & Target^[1]

MAO-B

170 nM (IC₅₀)

MAO-A

>1000 nM (IC₅₀)

All Monoamine Oxidase Isoforms :

MAO-A
MAO-B

In Vitro

MAO-B-IN-58 potently inhibits MAO-B in rat brain mitochondria with an IC₅₀ of 170 nM and does not inhibit MAO-A^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 898540-68-6
분자량 302.33
화학식 C₁₉H₁₄N₂O₂
SMILES

CC1=CC2=C(C3=CC(OCC4=CC=CC=C4)=CC=C3C2=O)N=N1
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Frédérick R, et al. Synthesis, structural reassignment, and biological activity of type B MAO inhibitors based on the 5H-indeno[1,2-c]pyridazin-5-one core. J Med Chem. 2006 Jun 15;49(12):3743-7. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
- IC₅₀ & Target
- In Vitro
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MAO-B-IN-58

All Monoamine Oxidase Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

MAO-B-IN-58 Related Classifications

HY-184026 Related Classifications