MEK-IN-7
MEK-IN-7 (compound WX086) is potent, orally active and selective MEK inhibitor (MEK1 IC50 = 29.62 nM). MEK-IN-7 inhibits HT29 and A375 cell proliferation with IC50s of 0.62 and 0.40 nM. MEK-IN-7 inhibits tumor growth in a HL-29 xenograft mouse model. MEK-IN-7 can be used for melanoma and colon cancer research.
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- CAS No.: 2256822-22-5
- 화학식: C27H25FIN3O5S
- 분자량:649.47
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Biological Activity
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MEK1 29.62 nM (IC50) |
Chemical Information
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CAS No. 2256822-22-5
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분자량 649.47
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화학식 C27H25FIN3O5S
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SMILES
O=C1OC2=C(C(NC3=CC=C(C=C3F)I)=C1C)C(N(C4CC4)C(C)=C2C5=C(C)C(NS(C)(=O)=O)=CC=C5)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
MEK-IN-7 Related Classifications
HY-177914 Related Classifications
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