Mutant IDH1-IN-3
Mutant IDH1-IN-3 (Compound 1) is a selective allosteric inhibitor of mutant isocitrate dehydrogenase 1 (IDH1). Mutant IDH1-IN-3 has an IC50 of 13 nM for R132H IDH1. Mutant IDH1-IN-3 inhibits the production of D-2-hydroxyglutaric acid (2HG) in cells. Mutant IDH1-IN-3 can be used in the study of cancer.
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- CAS No.: 1648909-73-2
- 화학식: C22H30N4O
- 분자량:366.50
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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R132H IDH1 13 nM (IC50) |
Chemical Information
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CAS No. 1648909-73-2
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분자량 366.50
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화학식 C22H30N4O
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SMILES
OC1=C(CN2C=CN=C2)C=C(C(C)(C)CC(C)(C)C)C=C1CN3C=CN=C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)