Mutant IDH1-IN-3

Mutant IDH1-IN-3 (Compound 1) is a selective allosteric inhibitor of mutant isocitrate dehydrogenase 1 (IDH1). Mutant IDH1-IN-3 has an IC50 of 13 nM for R132H IDH1. Mutant IDH1-IN-3 inhibits the production of D-2-hydroxyglutaric acid (2HG) in cells. Mutant IDH1-IN-3 can be used in the study of cancer.

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  • CAS No.: 1648909-73-2
  • 화학식: C22H30N4O
  • 분자량:366.50
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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All Isocitrate Dehydrogenase (IDH) Isoforms

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