PIM1-IN-6
PIM1-IN-6 (compound 5h) is a potent PIM-1 inhibitor, with an IC50 of 0.60 μM. PIM1-IN-6 shows the high cytotoxicity activity against HCT-116 and MCF-7 cells, with IC50 values of 1.51 and 15.2 μM, respectively.
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- CAS No.: 2439168-69-9
- 화학식: C21H18N6O4
- 분자량:418.41
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
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PIM1 0.60 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
1.51 μM
Compound: 44
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Anticancer activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
Anticancer activity against human HCT-116 cells assessed as inhibition of cell proliferation measured after 48 hrs by MTT assay
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[PMID: 34438126] |
Chemical Information
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CAS No. 2439168-69-9
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분자량 418.41
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화학식 C21H18N6O4
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SMILES
O=C(C1=C2NC(C=C(C3=CC=CC=C3)N2N=C1NCC)=O)NC4=CC=C([N+]([O-])=O)C=C4
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PIM1-IN-6 Related Classifications
HY-147920 Related Classifications
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