Antibiotics from basidiomycetes. IX. Oudemansin, an antifungal antibiotic from Oudemansiella mucida (Schrader ex Fr.) Hoehnel (Agaricales)

  • J Antibiot (Tokyo). 1979 Nov;32(11):1112-7. doi: 10.7164/antibiotics.32.1112.
T Anke ,  H J Hecht ,  G Schramm ,  W Steglich
PMID: 528381 DOI: 10.7164/antibiotics.32.1112
Abstract

From mycelial cultures of Oudemansiella mucida a crystalline optically active Antibiotic, oudemansin (2), has been isolated; its structure is closely related to strobilurin A (1). The relative configuration of oudemansin have been determined by X-ray analysis. The Antibiotic exhibits strong Antifungal properties and inhibits respiration in fungi, cells of the ascitic form of EHRLICH carcinoma, and rat liver mitochondria.

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