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Cat. No.: HY-103330

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TC-C 14G

TC-C 14G (Compd 14g) is a Cannabinoid-1 Receptor (CB1R) inverse agonist, with a K_i of 4 nM and EC₅₀ of 11 nM for HCB1R, respectively.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 656804-72-7
화학식: C₂₄H₁₇Cl₂F₂NO₄
분자량:492.30

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

TC-C 14G Chemical Structure

CAS No.: 656804-72-7

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

TC-C 14G (Compd 14g) is a Cannabinoid-1 Receptor (CB1R) inverse agonist, with a K_i of 4 nM and EC₅₀ of 11 nM for HCB1R, respectively^[1].

All Cannabinoid Receptor Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
HEK293	EC₅₀	11 nM Compound: 14g	Activity at human CB1R expressed in HEK293 cells assessed as intracellular cAMP level Activity at human CB1R expressed in HEK293 cells assessed as intracellular cAMP level	[PMID: 18335976]

Chemical Information

CAS No. 656804-72-7
분자량 492.30
화학식 C₂₄H₁₇Cl₂F₂NO₄
SMILES

O=C(C1=C(F)C=C(OC(C2=CC=C(F)C=C2)(C3=CC=C(Cl)C=C3Cl)O4)C4=C1)N5CCOCC5
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Leo Alig, et al. Benzodioxoles: novel cannabinoid-1 receptor inverse agonists for the treatment of obesity. J Med Chem. 2008 Apr 10;51(7):2115-27. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Biological Activity
- 제품 설명
Chemical Information
순도&문서
References

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TC-C 14G

All Cannabinoid Receptor Isoforms

Biological Activity

Chemical Information

순도&문서

References

Calculators

Help & FAQs

TC-C 14G Related Classifications

HY-103330 Related Classifications