2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. Potassium Channel Calcium Channel
  4. Lidoflazine

Lidoflazine is a high affinity blocker of the HERG (human ether-a-go-go-related gene) K+ channel. Lidoflazine is an antianginal calcium channel blocker that carries a significant risk of QT interval prolongation and ventricular arrhythmia.

For research use only. We do not sell to patients.

Lidoflazine Chemical Structure

Lidoflazine Chemical Structure

CAS No. : 3416-26-0

Size Price Stock
Solution
10 mM * 1 mL in DMSO USD 946 Ask For Quote & Lead Time
Solid
5 mg USD 537 Ask For Quote & Lead Time
10 mg USD 860 Ask For Quote & Lead Time

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Lidoflazine Related Antibodies

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Description

Lidoflazine is a high affinity blocker of the HERG (human ether-a-go-go-related gene) K+ channel. Lidoflazine is an antianginal calcium channel blocker that carries a significant risk of QT interval prolongation and ventricular arrhythmia[1].

In Vitro

Lidoflazine inhibits potently HERG current (IHERG) recorded from HEK 293 cells stably expressing wild-type HERG (IC50 of ~16 nM).

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Lidoflazine Related Antibodies
Molecular Weight

491.62

Formula

C30H35F2N3O
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NC1=C(C)C=CC=C1C)CN2CCN(CCCC(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)CC2
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Purity & Documentation

Purity: ≥98.0%

COA (244 KB)

Handling Instructions (2659 KB)
References
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Lidoflazine Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lidoflazine3416-26-0Potassium ChannelCalcium ChannelKcsACa2+ channelsCa channelsInhibitorinhibitorinhibit

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