3416-26-0
3416-26-0
Chemical Structure
Lidoflazine
- CAS No.: 3416-26-0
- Formula:C30H35F2N3O
- Molecular Weight:491.62
IUPAC Name: 2-(4-(4,4-bis(4-fluorophenyl)butyl)piperazin-1-yl)-N-(2,6-dimethylphenyl)acetamide
InChIKey: ZBIAKUMOEKILTF-UHFFFAOYSA-N
SMILES: O=C(NC1=C(C)C=CC=C1C)CN2CCN(CCCC(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)CC2
Biological Activity: Lidoflazine is a high affinity blocker of the HERG (human ether-a-go-go-related gene) K+ channel. Lidoflazine is an antianginal calcium channel blocker that carries a significant risk of QT interval prolongation and ventricular arrhythmia[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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Lidoflazine | 99.40% | Lidoflazine is a high affinity blocker of the HERG (human ether-a-go-go-related gene) K+ channel. Lidoflazine is an antianginal calcium channel blocker that carries a significant risk of QT interval prolongation and ventricular arrhythmia. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.69
HY-U00049Mioflazine -
Similarity Score 0.68
HY-U00049BMioflazine dihydrochloride -
Similarity Score 0.68
HY-U00049AMioflazine (di(hydrochloride) hydrate) -
Similarity Score 0.68
HY-121301Amperozide -
Similarity Score 0.63
HY-106841Draflazine -
Similarity Score 0.63
HY-106841A(S)-Draflazine -
Similarity Score 0.62
HY-13217AVanoxerine -
Similarity Score 0.61
HY-U00005AD 0261 -
Similarity Score 0.61
HY-W518419Ranolazine impurity 3 -
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