Mioflazine (di(hydrochloride) hydrate)
Mioflazine dihydrochloride hydrate is a nucleoside transport inhibitor with sleep-improving activity. Mioflazine dihydrochloride hydrate helps maintain the mechanical function of the left ventricle and significantly improves the heart's recovery ability after global ischemia at new temperatures. Mioflazine dihydrochloride hydrate reduces the mitochondrial calcium content in guinea-pig.
For research use only. We do not sell to patients.
- CAS No.: 79467-24-6
- Formula: C29H34Cl4F2N4O3
- Molecular Weight:666.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
Chemical Information
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CAS No. 79467-24-6
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Molecular Weight 666.41
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Formula C29H34Cl4F2N4O3
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SMILES
O=C(C1N(CCCC(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F)CCN(C1)CC(NC4=C(Cl)C=CC=C4Cl)=O)N.Cl.Cl.O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Wauquier A, et al. Sleep improvement in dogs after oral administration of mioflazine, a nucleoside transport inhibitor. Psychopharmacology (Berl). 1987;91(4):434-9. [Content Brief]
[2]. Mioflazine, a potentially protective drug against ischaemic damage: a study in dogs [Content Brief]
[3]. Pirovano IM, et al. Inhibition of nucleoside uptake in human erythrocytes by a new series of compounds related to lidoflazine and mioflazine. Eur J Pharmacol. 1990 Dec 15;189(6):419-22. [Content Brief]
[4]. J G Hugtenburg, et al. The influence of nifedipine and mioflazine on mitochondrial calcium overload in normoxic and ischaemic guinea-pig hearts. Eur J Pharmacol. 1990 Mar 13;178(1):71-8. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Mioflazine (di(hydrochloride) hydrate) Related Classifications
HY-U00049A Related Classifications
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