2. GPCR/G Protein Neuronal Signaling
  3. 5-HT Receptor
  4. Amperozide

Amperozide is an atypical antipsychotic that acts as an antagonist of the 5-HT2 receptor with a Ki value of 26 nM. Amperozide has a low affinity for D2 receptors.

For research use only. We do not sell to patients.

Amperozide Chemical Structure

Amperozide Chemical Structure

CAS No. : 75558-90-6

Size Price Stock Quantity
5 mg USD 250 In-stock
10 mg USD 400 In-stock
50 mg   Get quote  
100 mg   Get quote  

* Please select Quantity before adding items.

This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

Amperozide Related Antibodies

Top Publications Citing Use of Products

View All 5-HT Receptor Isoform Specific Products:

View All Isoforms

  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Amperozide is an atypical antipsychotic that acts as an antagonist of the 5-HT2 receptor with a Ki value of 26 nM. Amperozide has a low affinity for D2 receptors[1].

IC50 & Target

5-HT2A Receptor

26 nM (Ki)

Molecular Weight

401.49

Formula

C23H29F2N3O
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(NCC)N1CCN(CC1)CCCC(C2=CC=C(C=C2)F)C3=CC=C(C=C3)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (311.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4907 mL 12.4536 mL 24.9072 mL
5 mM 0.4981 mL 2.4907 mL 4.9814 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.4907 mL 12.4536 mL 24.9072 mL 62.2681 mL
5 mM 0.4981 mL 2.4907 mL 4.9814 mL 12.4536 mL
10 mM 0.2491 mL 1.2454 mL 2.4907 mL 6.2268 mL
15 mM 0.1660 mL 0.8302 mL 1.6605 mL 4.1512 mL
20 mM 0.1245 mL 0.6227 mL 1.2454 mL 3.1134 mL
25 mM 0.0996 mL 0.4981 mL 0.9963 mL 2.4907 mL
30 mM 0.0830 mL 0.4151 mL 0.8302 mL 2.0756 mL
40 mM 0.0623 mL 0.3113 mL 0.6227 mL 1.5567 mL
50 mM 0.0498 mL 0.2491 mL 0.4981 mL 1.2454 mL
60 mM 0.0415 mL 0.2076 mL 0.4151 mL 1.0378 mL
80 mM 0.0311 mL 0.1557 mL 0.3113 mL 0.7784 mL
100 mM 0.0249 mL 0.1245 mL 0.2491 mL 0.6227 mL
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.

Amperozide Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Amperozide75558-90-65-HT ReceptorSerotonin Receptor5-hydroxytryptamine Receptor5-HT2AntagonistD2AntipsychoticInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

  

Salutation

Applicant Name *

 

Email Address *

Phone Number *

 

Organization Name *

Department *

 

Requested quantity *

Country or Region *

      

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Amperozide
Cat. No.:
HY-121301
Quantity:
MCE Japan Authorized Agent:

Customer Review

Thank You for Your Feedback!

Request for HNMR Report

Please fill out this form to request the QC report. We will send it to your Email address shortly.

Your information is safe with us. * Required Fields.

Product Name

  

Lot #

Applicant Name *

 

Email Address *

Phone Number

 

Department *

Organization Name *

 

Country or Region *

Remarks

Request for HNMR Report

We have received your request and will respond to you as soon as possible.