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Cat. No.: HY-168541

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Pomalidomide-N-Glutarylglycine

Pomalidomide-N-Glutarylglycine is a E3 ligase ligand-linker conjugate that can be used in the synthesis of PROTACT (HY-168540).

For research use only. We do not sell to patients.

Formula: C₂₀H₂₀N₄O₈
Molecular Weight:444.39

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Pomalidomide-N-Glutarylglycine Chemical Structure

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Pomalidomide-N-Glutarylglycine is a E3 ligase ligand-linker conjugate that can be used in the synthesis of PROTACT (HY-168540)^[1].

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

Molecular Weight 444.39
Formula C₂₀H₂₀N₄O₈
SMILES

O=C(NCC(O)=O)CCCC(NC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sflakidou E, et, al. Development of 2-Aminoadenine-Based Proteolysis-Targeting Chimeras (PROTACs) as Novel Potent Degraders of Monopolar Spindle 1 and Aurora Kinases. ACS Pharmacol. Transl. Sci. 2024.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
Chemical Information
Purity & Documentation
References

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Pomalidomide-N-Glutarylglycine

All E3 Ligase Ligand-Linker Conjugates Isoforms