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dc-sign-cd209

" in MedChemExpress (MCE) Product Catalog:

By Targets:	C-type Lectin-like Receptors (CTLRs) (1) Integrin (1) Toll-like Receptor (TLR) (1)
By Research Areas:	Cancer (1) Inflammation/Immunology (1)
Click Chemistry:	Alkynes (1)

Inhibitors & Agonists

Inhibitory Antibodies

Recombinant Proteins

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Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-P990398

*Anti-DC-SIGN/CD209* Antibody**	Integrin C-type Lectin-like Receptors (CTLRs)	Inflammation/Immunology
Anti-DC-SIGN/CD209 Antibody is a CHO-expressed humanized antibody that targets *DC-SIGN/CD209. Anti-DC-SIGN/CD209* Antibody is composed of huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 146.62 kDa. The isotype control for Anti-DC-SIGN/CD209 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

HY-175421

ArMan	Toll-like Receptor (TLR)	Cancer
ArMan is a co-activator of *DC-SIGN* (CD209) and TLR7. ArMan can selectively bind to DC-SIGN, promoting receptor-mediated endocytosis of the virus-like particle (VLP) platform, thereby enhancing co-binding with TLR7. ArMan can drive dendritic cell activation, shifting the immune response from humoral immunity to type 1 cellular immunity. ArMan can be used in melanoma research .

Cat. No.	Product Name	Target	Research Area	Image

HY-P990398

*Anti-DC-SIGN/CD209* Antibody**	Integrin C-type Lectin-like Receptors (CTLRs)	Inflammation/Immunology
Anti-DC-SIGN/CD209 Antibody is a CHO-expressed humanized antibody that targets *DC-SIGN/CD209. Anti-DC-SIGN/CD209* Antibody is composed of huIgG1 heavy chain and huκ light chain, with a predicted molecular weight (MW) of 146.62 kDa. The isotype control for Anti-DC-SIGN/CD209 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).

Species:	Human (2) Rhesus Macaque (2) Mouse (1)
Tag:	His (3) Fc (2)
Source:	HEK293 (5)

Cat. No.	Compare	Product Name	Species	Source	Image

HY-P76643

	DC-SIGN/CD209 Protein, Mouse (HEK293, His) cd209 antigen; dc-sign1; cd209	Mouse	HEK293
	DC-SIGN/CD209 Protein, a probable pathogen-recognition receptor, mediates the endocytosis and lysosomal degradation of pathogens. It recognizes high mannose N-linked oligosaccharides in pathogen antigens in a calcium-dependent manner and functions as a receptor for ICAM3, potentially through binding to mannose-like carbohydrates. DC-SIGN/CD209 Protein, Mouse (HEK293, His) is the recombinant mouse-derived DC-SIGN/CD209 protein, expressed by HEK293 , with N-His labeled tag.

HY-P74205

	DC-SIGN/CD209 Protein, Rhesus Macaque (HEK293, His) cd209 antigen; dc-sign1; cd209	Rhesus Macaque	HEK293
	DC-SIGN/CD209 Protein, is a C-type lectin receptor present on the surface of both macrophages and dendritic cells (DCs), serves as a pivotal pathogen-recognition receptor, playing a crucial role in initiating the primary immune response. It mediates endocytosis and subsequent degradation of pathogens within lysosomal compartments. On DCs, it acts as a high-affinity receptor for ICAM2 and ICAM3, binding to mannose-like carbohydrates. DC-SIGN/CD209 Protein, Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived DC-SIGN/CD209 protein, expressed by HEK293 , with N-His labeled tag.

HY-P74206

	DC-SIGN/CD209 Protein, Rhesus Macaque (HEK293, Fc) cd209 antigen; dc-sign1; cd209	Rhesus Macaque	HEK293
	DC-SIGN/CD209 Protein, is a C-type lectin receptor present on the surface of both macrophages and dendritic cells (DCs), serves as a pivotal pathogen-recognition receptor, playing a crucial role in initiating the primary immune response. It mediates endocytosis and subsequent degradation of pathogens within lysosomal compartments. On DCs, it acts as a high-affinity receptor for ICAM2 and ICAM3, binding to mannose-like carbohydrates. DC-SIGN/CD209 Protein, Rhesus Macaque (HEK293, Fc) is the recombinant Rhesus Macaque-derived DC-SIGN/CD209 protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P70110

	DC-SIGN/CD209 Protein, Human (HEK293, Fc) rHucd209 antigen/cd209, Fc; cd209 molecule; cd209; cdsignHIV gpl20-binding protein; CLEC4L; dcsign; dc-sign; dc-sign1; cd209 Antigen	Human	HEK293
	The DC-SIGN/CD209 protein is expressed on immature dendritic cells (DC) and is an important pathogen recognition receptor that initiates primary immune responses. It mediates endocytosis and subsequent degradation of pathogens within the lysosomal compartment. DC-SIGN/CD209 Protein, Human (HEK293, Fc) is the recombinant human-derived DC-SIGN/CD209 protein, expressed by HEK293 , with N-hFc labeled tag.

HY-P704561

	DC-SIGN/CD209 Protein, Human (HEK293, His) rHucd209 antigen/cd209, Fc; cd209 molecule; cd209; cdsignHIV gpl20-binding protein; CLEC4L; dcsign; dc-sign; dc-sign1; cd209 Antigen	Human	HEK293
	The DC-SIGN/CD209 protein is expressed on immature dendritic cells (DC) and is an important pathogen recognition receptor that initiates primary immune responses. It mediates endocytosis and subsequent degradation of pathogens within the lysosomal compartment. DC-SIGN/CD209 Protein, Human (HEK293, His) is the recombinant human-derived DC-SIGN/CD209 protein, expressed by HEK293, with N-His labeled tag.

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Cat. No.	Product Name		Classification

HY-175421

ArMan		Alkynes
ArMan is a co-activator of *DC-SIGN* (CD209) and TLR7. ArMan can selectively bind to DC-SIGN, promoting receptor-mediated endocytosis of the virus-like particle (VLP) platform, thereby enhancing co-binding with TLR7. ArMan can drive dendritic cell activation, shifting the immune response from humoral immunity to type 1 cellular immunity. ArMan can be used in melanoma research .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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