GRO-gamma

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CXCL3 is also known as MIP-2 beta, or DCIP-1 in mouse, CINC2 in rat, and GRO-gamma in humans. CXCL3 is a member of the CXC chemokine subfamily, and it is subclassified as a Glu-Leu-Arg (ELR+) CXC chemokine. CXCL3 is a chemoattractant for neutrophils and belongs to CXC chemokine subfamily. CXCL3 is a secreted growth factor that signals through its cognate receptor CXCR2. CXCL3 is involved in many immune responses including wound healing, cancer metastasis, and angiogenesis^[1]^[2].
CXCL3 plays an important role in leukocyte chemotaxis, angiogenesis, tumorigenesis, and cell invasion. CXCL3 exerts its functions through a number of signaling pathways including p38 MAPK, ERK1/2 MAPK and JAK2/STAT3 etc., by activating CXCR2 receptor. CXCL3 is highly expressed during the number of tumorous conditions including melanoma, prostate, colorectal, aggressive breast cancer tumors, hepatocellular carcinoma (HCC) and also during hepatic injury and inflammation^[3]^[4].

References:

[1]. Niradiz Reyes, et al. CXCL3 Signaling in the Tumor Microenvironment. Adv Exp Med Biol. 2021;1302:15-24. [Content Brief]

[2]. Joji Kusuyama, et al. CXCL3 positively regulates adipogenic differentiation. J Lipid Res. 2016 Oct;57(10):1806-1820. [Content Brief]

[3]. Khushboo Gulati, et al. Molecular cloning and biophysical characterization of CXCL3 chemokine. Int J Biol Macromol. 2018 Feb;107(Pt A):575-584. [Content Brief]

[4]. Jinru Weng, et al. CXCL3 overexpression affects the malignant behavior of oral squamous cell carcinoma cells via the MAPK signaling pathway. J Oral Pathol Med. 2021 Oct;50(9):902-910. [Content Brief]

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GRO-gamma Recombinant Proteins (9)

Species:	Human (4) Mouse (4) Rat (1)
Tag:	His (3) Tag Free (6)
Source:	E. coli (5) CHO (3) P. pastoris (1)

Cat. No.	Product Name / Synonyms	Species	Source

HY-P7192

GRO-gama/CXCL3 Protein, Human (CHO) rHuGRO-γ/CXCL3; C-X-C motif chemokine 3; MIP2-beta	Human	CHO
CXCL3 is a chemoattractant for neutrophils and belongs to CXC chemokine subfamily. CXCL3 is a secreted growth factor that signals through its cognate receptor CXCR2. CXCL3 is involved in many immune responses including wound healing, cancer metastasis, and angiogenesis. GRO-gama/CXCL3 Protein, Human (CHO) is produced in CHO cells, and consists of 73 amino acids (A35-N107).

HY-P72678

GRO-gama/CXCL3 Protein, Human (His) C-X-C motif chemokine 3; GRO-gamma; MIP2-beta; CXCL3; GRO3; GROG; SCYB3	Human	E. coli
CXCL3 is a chemoattractant for neutrophils and belongs to CXC chemokine subfamily. CXCL3 is a secreted growth factor that signals through its cognate receptor CXCR2. CXCL3 is involved in many immune responses including wound healing, cancer metastasis, and angiogenesis. GRO-gama/CXCL3 Protein, Human (His) is produced in E. coli with six N-Terminal His-tags. It consists of 73 amino acids (A35-N107).

HY-P7152

CXCL3/CINC-2 alpha Protein, Rat (CHO) rRtCXCL3; C-X-C motif chemokine 3; Cytokine-induced neutrophil chemoattractant 2; CINC-2; MIP2-alpha/beta	Rat	CHO
CXCL3 is a chemoattractant for neutrophils and belongs to CXC chemokine subfamily. CXCL3 is a secreted growth factor that signals through its cognate receptor CXCR2. CXCL3 is involved in many immune responses including wound healing, cancer metastasis, and angiogenesis. CXCL3 Protein, Rat (CHO) is produced in CHO cells, and consists of 68 amino acids (R33-S100).

HY-P7193

GRO-gama/CXCL3 Protein, Human rHuGRO-γ/CXCL3; C-X-C motif chemokine 3; MIP2-beta	Human	E. coli
CXCL3 is a chemoattractant for neutrophils and belongs to CXC chemokine subfamily. CXCL3 is a secreted growth factor that signals through its cognate receptor CXCR2. CXCL3 is involved in many immune responses including wound healing, cancer metastasis, and angiogenesis. GRO-gama/CXCL3 Protein, Human is produced in E. coli , and consists of 73 amino acids (A35-N107).

HY-P7337

DCIP-1/CXCL3 Protein, Mouse (P.pastoris) rMuDCIP-1/CXCL3; C-X-C motif chemokine 3; Dendritic cell inflammatory protein 1	Mouse	P. pastoris
CXCL3 is a chemoattractant for neutrophils and belongs to CXC chemokine subfamily. CXCL3 is a secreted growth factor that signals through its cognate receptor CXCR2. CXCL3 is involved in many immune responses including wound healing, cancer metastasis, and angiogenesis. DCIP-1/CXCL3 Protein, Mouse (P.pastoris) is produced in P.pastoris , and consists of 73 amino acids (A28-S100).

HY-P72678AF

Animal-Free GRO-gama/CXCL3 Protein, Human (His) C-X-C motif chemokine 3; GRO-gamma; MIP2-beta; CXCL3; GRO3; GROG; SCYB3	Human	E. coli
The GRO-gama/CXCL3 Protein, acting as a CXCR2 ligand, induces chemotactic activity for neutrophils. It potentially influences inflammation through autocrine effects on endothelial cells. In vitro studies highlight the processed form GRO-gamma(5-73)'s fivefold increase in chemotactic activity for neutrophilic granulocytes, indicating a potential regulatory mechanism for neutrophil recruitment and function. Animal-Free GRO-gama/CXCL3 Protein, Human (His) is the recombinant human-derived animal-FreeGRO-gama/CXCL3 protein, expressed by E. coli , with N-His, N-His labeled tag. The total length of Animal-Free GRO-gama/CXCL3 Protein, Human (His) is 73 a.a., with molecular weight of ~8.67 kDa.

HY-P7153

DCIP-1/CXCL3 Protein, Mouse rMuCXCL3; C-X-C motif chemokine 3; Dendritic cell inflammatory protein 1; DCIP-1	Mouse	E. coli
CXCL3 is a chemoattractant for neutrophils and belongs to CXC chemokine subfamily. CXCL3 is a secreted growth factor that signals through its cognate receptor CXCR2. CXCL3 is involved in many immune responses including wound healing, cancer metastasis, and angiogenesis. DCIP-1/CXCL3 Protein, Mouse is produced in E. coli , and consists of 73 amino acids (A28-S100).

HY-P700172AF

Animal-Free DCIP-1/CXCL3 Protein, Mouse (His) rMuDCIP-1/CXCL3; C-X-C motif chemokine 3; Dendritic cell inflammatory protein 1	Mouse	E. coli
DCIP-1/CXCL3 Protein, a CXCR2 ligand, exhibits chemotactic activity for neutrophils, implicating its role in inflammation. It may autonomously affect endothelial cells. The protein's chemotactic activity implies a potential regulatory role in recruiting and activating neutrophils in response to inflammatory stimuli. Animal-Free DCIP-1/CXCL3 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeDCIP-1/CXCL3 protein, expressed by E. coli , with N-His labeled tag. The total length of Animal-Free DCIP-1/CXCL3 Protein, Mouse (His) is 73 a.a., with molecular weight of ~8.72 kDa.

HY-P700003

DCIP-1/CXCL3 Protein, Mouse (CHO) rMuDCIP-1/CXCL3; C-X-C motif chemokine 3; Dendritic cell inflammatory protein 1	Mouse	CHO
DCIP-1/CXCL3 Protein, Mouse (CHO) acts as a chemoattractant for neutrophils and is involved in the inflammatory response produced in CHO cells.

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GRO-gamma

GRO-gamma

Subscribe Now to the List of Recombinant Proteins

GRO-gamma Recombinant Proteins (9)