26 Results for "

H3-2

" in MedChemExpress (MCE) Product Catalog:
Products (26)

26 Results for "H3-2" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-19408
CAS No.: 1315323-00-2
Target:  

TRP Channel

Domaines de recherche:  

Others

Pyr10 is a pyrazole derivative and a selective TRP cation 3 (TRPC3) inhibitor. Pyr10 inhibits Ca 2+ influx in carbachol-stimulated TRPC3-transfected HEK293 cells with an IC50 of 0.72 μM (IC50 of 13.08 μM for store operated Ca 2+ entry in BRL-2H3 cells). Pyr10 has the ability to distinguish between receptor-operated TRPC3 and native stromal interaction molecule 1 (STIM1)/Orai1 channels .
Cat. No.: HY-N2252
CAS No.: 51020-86-1
Synonyms: (+)-Licarin A
Licarin A ((+)-Licarin A), a neolignan, significantly and dose-dependently reduces TNF-α production (IC50=12.6 μM) in dinitrophenyl-human serum albumin (DNP-HSA)-stimulated RBL-2H3 cells. Anti-allergic effects. Licarin A reduces TNF-α and PGD2 production, and COX-2 expression .
Cat. No.: HY-W081085
CAS No.: 914637-49-3
Domaines de recherche:  

Others

2H,2H,3H,3H-Perfluorooctanoic acid (4,4,5,5,6,6,7,7,8,8,8-Undecafluorooctanoic acid) is a biological molecule.
Cat. No.: HY-15086
CAS No.: 110347-85-8
Pureté:  99.67%
Synonyms: CGS 19755
Target:  

iGluR

Domaines de recherche:  

Neurological Disease

Selfotel (CGS 19755) is a selective and competitive antagonist at N-methyl-D-aspartate (NMDA)-preferring receptor. CGS 19755 inhibits the binding of [3H]-3-(2-carboxypiperazin-4-yl)propyl-1-phosphonic acid to NMDA-type receptors with an IC50 of 50 nM .
Cat. No.: HY-RS05967
Domaines de recherche:  

Others

H3C14 Human Pre-designed siRNA Set A contains three designed siRNAs for H3C14 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-P1640
CAS No.: 130154-64-2
Target:  

Complement System

Domaines de recherche:  

Inflammation/Immunology

(Trp63,Trp64)​-​C3a(63-77) is a C3a synthetic analogue peptide, which exhibits Ca 2+ stimulating efficacy in human neutrophils and hC3aR or mC3aR expressing RBL-2H3 cells with EC50 of 9.5, 2.0 and 0.8 nM, respectively .
Cat. No.: HY-N15708
CAS No.: 755036-45-4
Synonyms: (R)-(-)-Dichotomine C
Dichotomine C ((R)-(-)-Dichotomine C) is a β-carboline-type alkaloid with antiallergic effects. Dichotomine C inhibits the release of β-hexosaminidase in RBL-2H3 cells with an IC50 of 62 μM. Dichotomine C inhibits the releases of antigen-IgE-mediated TNF-α and IL-4 in RBL-2H3 cells with IC50s of 19 μM and 15 μM, respectively. Dichotomine C can be used for the study of type I allergic reactions .
Cat. No.: HY-RS05965
Domaines de recherche:  

Others

H3-7 Human Pre-designed siRNA Set A contains three designed siRNAs for H3-7 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Cat. No.: HY-N12116
CAS No.: 1967042-42-7
Maceneolignan A is a natural product that can be isolated from mace, the aril of Myristica fragrans (Myristicaceae). Maceneolignan A inhibits the release of β-hexosaminidase in RBL-2H3 cells, with an IC50 of 48.4 μM. Maceneolignan A inhibits the release of TNF-α in antigen stimulated RBL-2H3 cells, with an IC50 of 63.7 μM .
Cat. No.: HY-N8426
CAS No.: 79004-25-4
Synonyms: Ellisinin A
4'-O-Methylnyasol is an inhibitor of β-hexosaminidase. 4'-O-Methylnyasol inhibits β-hexosaminidase release from rat basophilic leukemia-2H3 cells with an IC50 of 52.67 μM .
Cat. No.: HY-139247
CAS No.: 2454246-25-2
Target:  

Drug Derivative

Domaines de recherche:  

Inflammation/Immunology

pNPS-DHA (Compound 19) is an orally active DHA-ethanolamide (DHEA) derivative that has antiallergic activity. pNPS-DHA inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) reaction in mice. pNPS-DHA has anti-degranulating activity in RBL-2H3 mast cells with an IC50 of 15 μM .
Cat. No.: HY-P11128
CAS No.: 1427516-68-4
Target:  

Peptides

Domaines de recherche:  

Others

Mastoparan-V1 is a peptide belonging to the Mastoparan family. Mastoparan-V1 exhibits modest mast cell degranulation activity, with EC50 of 130.24 μM in RBL-2H3 cells. Mastoparan-V1 can be used for the study of allergic reactions induced by wasp stings .
Cat. No.: HY-P11163
CAS No.: 255720-68-4
Target:  

Bacterial Glycosidase

Domaines de recherche:  

Infection

Eumenitin is an antibacterial peptide with strong membrane activity, broad-spectrum antibacterial activity, and almost no hemolytic toxicity. Eumenitin has inhibitory effects on various Gram positive and Gram negative bacteria. Eumenitin can induce the release of β-hexosaminidase from rat peritoneal mast cells and RBL-2H3 cells. Eumenitin can be used in the research of infectious conditions .
Cat. No.: HY-154613
CAS No.: 142189-87-5
Domaines de recherche:  

Cancer

(2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc .
Cat. No.: HY-116295
CAS No.: 7077-89-6
Domaines de recherche:  

Cardiovascular Disease

MRS2690 is a selective P2Y14 receptor agonist. MRS2690 inhibits adenylyl cyclase activity, thereby reducing intracellular cAMP levels and mediating concentration-dependent vasoconstriction of porcine coronary arteries. MRS2690 induces intracellular calcium mobilization, activates P38 and stimulates [ 35S]GTPγS binding to RBL-2H3 cell membranes. MRS2690 enhances antigen (NP-BSA)-, C3a-induced β-hexosaminidase (β-Hex) release. MRS2690can be used for ischemic heart disease .
Cat. No.: HY-116295A
Domaines de recherche:  

Cardiovascular Disease

MRS2690 disodium is a selective P2Y14 receptor agonist. MRS2690 disodium inhibits adenylyl cyclase activity, thereby reducing intracellular cAMP levels and mediating concentration-dependent vasoconstriction of porcine coronary arteries. MRS2690 disodium induces intracellular calcium mobilization, activates P38 and stimulates [ 35S]GTPγS binding to RBL-2H3 cell membranes. MRS2690 enhances antigen (NP-BSA)-, C3a-induced β-hexosaminidase (β-Hex) release. MRS2690 disodium can be used for ischemic heart disease .
Cat. No.: HY-P84652
Synonyms: H3; H3.2; H3/M; H3F2; H3FM; H3FN

Host:  

Mouse

Application:  

WB, IHC-P, FC, ELISA

Reactivity:  

Human

Cat. No.: HY-P84652A
Synonyms: H3; H3.2; H3/M; H3F2; H3FM; H3FN

Host:  

Mouse

Application:  

WB, IHC-P, FC, ELISA

Reactivity:  

Human

Cat. No.: HY-W422312
CAS No.: 37881-74-6
Target:  

MOFs

Domaines de recherche:  

Others

2,2'-(1,3,5,7-Tetraoxo-5,7-dihydropyrrolo[3,4-f]isoindole-2,6(1H,3H)-diyl)dibenzoic acid is a metal-organic framework (MOF).
Cat. No.: HY-P86113
Synonyms: H3K4ME2; HIST1H3A; H3FA; HIST1H3B; H3FL; HIST1H3C; H3FC; HIST1H3D; H3FB; HIST1H3E; H3FD; HIST1H3F; H3FI; HIST1H3G; H3FH; HIST1H3H; H3FK; HIST1H3I; H3FF; HIST1H3J; H3FJ; Histone H3.1; Histone H3.1; Histone H3.2; Histone H3/m; Histone H3/o; H3F3A; H3.3A; H3F3; PP781; H3F3B; H3.3B; Histone H3.3; H3F3C; Histone H3.3C; Histone H3.5

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, IP, ELISA

Reactivity:  

Human, Mouse, Rat