142189-87-5
![(2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione Chemical Structure](http://file.medchemexpress.cn/product_pic/hy-154613.gif "(2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione Chemical Structure")
142189-87-5
Chemical Structure
(2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione
- CAS No.: 142189-87-5
- Formula:C9H10N2O5
- Molecular Weight:226.19
IUPAC Name: 5-((2R,5R)-5-(hydroxymethyl)-4-oxotetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
InChIKey: XNNRBPBGCPXKGR-RNFRBKRXSA-N
SMILES: OC[C@@H]1C(C[C@H](C(C(N2)=O)=CNC2=O)O1)=O
Biological Activity: (2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
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(2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione | (2R-cis)-5-[Tetrahydro-5-(hydroxymethyl)-4-oxo-2-furanyl]-2,4(1H,3H)-pyrimidinedione is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc. | |||||||||||||||||||||
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