2454246-25-2
2454246-25-2
Chemical Structure
pNPS-DHA
- CAS No.: 2454246-25-2
- Formula:C28H36N2O5S
- Molecular Weight:512.66
IUPAC Name: (4Z,7Z,10Z,13Z,16Z,19Z)-N-((4-nitrophenyl)sulfonyl)docosa-4,7,10,13,16,19-hexaenamide
InChIKey: VDIWFKLOBZZOII-KUBAVDMBSA-N
SMILES: CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCC(NS(=O)(C1=CC=C([N+]([O-])=O)C=C1)=O)=O
Biological Activity: pNPS-DHA (Compound 19) is an orally active DHA-ethanolamide (DHEA) derivative that has antiallergic activity. pNPS-DHA inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) reaction in mice. pNPS-DHA has anti-degranulating activity in RBL-2H3 mast cells with an IC50 of 15 μM[1].
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pNPS-DHA | pNPS-DHA (Compound 19) is an orally active DHA-ethanolamide (DHEA) derivative that has antiallergic activity. pNPS-DHA inhibits IgE-dependent passive cutaneous anaphylaxis (PCA) reaction in mice. pNPS-DHA has anti-degranulating activity in RBL-2H3 mast cells with an IC50 of 15 μM. | |||||||||||||||||||||
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