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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
147687
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "147687" in MCE Product Catalog:
6
6 Publications Verification
Synonyms: ABT-627; (+)-A 127722; A-147627
Target:
Forschungsgebiete:
Atrasentan (ABT-627) is an endothelin receptor antagonist with IC50 of 0.0551 nM for ETA .
6
6 Publications Verification
Synonyms: ABT-627 hydrochloride; (+)-A 127722 hydrochloride; A-147627 hydrochloride
Target:
Forschungsgebiete:
Atrasentan hydrochloride (ABT-627 hydrochloride) is a selective endothelin A receptor antagonist with an IC50 of 0.0551 nM for ETA .
2
2 Cited Publications
Synonyms: TMC120; R147681
Target:
Forschungsgebiete:
Dapivirine (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI). Dapivirine (TMC120) binds directly to HIV-1 reverse transcriptase. Dapivirine (TMC120) regulates autophagy and induced Akt, Bad and SAPK/JNK activations .
Art. -Nr.: HY-14266R
CAS. Nr.: 244767-67-7
Synonyms: TMC120 (Standard); R147681 (Standard)
Forschungsgebiete:
Dapivirine (Standard) is the analytical standard of Dapivirine. This product is intended for research and analytical applications. Dapivirine (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI). Dapivirine (TMC120) binds directly to HIV-1 reverse transcriptase. Dapivirine (TMC120) regulates autophagy and induced Akt, Bad and SAPK/JNK activations .
Art. -Nr.: HY-19284
CAS. Nr.: 146939-64-2
Synonyms: FK 687; TF 505
Target:
Forschungsgebiete:
FR-146687 (FK 687) is a selective and orally active 5α-reductase inhibitor with IC50s of 1.7 nM and 4.6 nM for rat and human 5α-reductases, respectively. FR-146687 shows no inhibitory effects on other steroid oxidoreductases .
Art. -Nr.: HY-14266S
CAS. Nr.: 1329613-10-6
Synonyms: TMC120-d11; R147681-d11
Art. -Nr.: HY-14266S1
CAS. Nr.: 1309283-15-5
Synonyms: TMC120-d4; R147681-d4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
