2 Results for "

1775-97-9

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "1775-97-9" in MCE Product Catalog:

2
Flavokawain B
Flavokawain B
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2 Cited Publications
Cat. No.: HY-N2132
CAS No.: 1775-97-9
Synonyms: Flavokavain B
Category:  

other families Flavonoids Chalcones Monophenols Phenols Plants Disease Research Fields Cancer

Target:  

Apoptosis Caspase PARP Bcl-2 Family NF-κB PI3K Akt p38 MAPK MMP Reactive Oxygen Species (ROS)

Flavokawain B (Flavokavain B) is an orally active chalcone. Flavokawain B results in activation of caspase-9, -3 and -8, cleavage of PARP. Flavokawain B down-regulates Bcl-2 with concomitant increase in Bax level. Flavokawain B inhibits NF-κB, PI3K/Akt and MAPK signaling pathway. Flavokawain B exhibits Apoptotic effects. Flavokawain B inhibits MMP-9 and promotes ROS generation. Flavokawain B inhibits multiple tumors and inflammation .
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Flavokawain B (Standard)
Flavokawain B (Standard)
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Cat. No.: HY-N2132R
CAS No.: 1775-97-9
Synonyms: Flavokavain B (Standard)
Category:  

other families Flavonoids Chalcones Monophenols Phenols Plants

Target:  

Reference Standards Apoptosis

Flavokawain B (Standard) is the analytical standard of Flavokawain B. This product is intended for research and analytical applications. Flavokawain B (Flavokavain B) is a chalcone isolated from the root extracts of kava-kava plant and a potent apoptosis inducer for inhibiting the growth of various cancer cell lines. Flavokawain B (Flavokavain B) shows strong antiangiogenic activity. Flavokawain B (Flavokavain B) inhibits human brain endothelial cell (HUVEC) migration and tube formation with very low and non-toxic concentrations .
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