3 Results for "

1O14

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "1O14" in MCE Product Catalog:

Cat. No.: HY-167015
CAS No.: 3117189-57-5
1O14 is an ionizable lipid. The ability of ionizable lipids to form unstable non-bilayer structures at acidic pH is key for endosomal escape and cytosolic delivery of RNA. 1O14 can be used in the preparation of liposomes .
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2
2 Cited Publications
Cat. No.: HY-137500
CAS No.: 2739805-64-0
Purity:  98.43%
NT1-O14B is a tryptamine-derived lipidoid. NT1-O14B incorporates NT-lipidoid into BBB-impermeable lipid nanoparticles (LNPs), enabling the LNPs to cross the BBB. NT1-O14B enhances brain delivery via intravenous injection. NT1-O14B can be used in ischemic stroke research .
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Cat. No.: HY-185778
CAS No.: 3027931-27-4
Target:  

Liposome

Research Areas:  

Others

PBA-Q76-O16B is a lipid that cannot cross the blood-brain barrier on its own, but can mediate cargo delivery into the brains of mice when blended with NT1 lipids. After forming stable small-sized lipid nanoparticles with NT1-O12B, PBA-Q76-O16B delivers drugs into the brains of mice. When formulated into lipid nanoparticles with NT1-O14B, PBA-Q76-O16B delivers (-27) GFP-Cre recombinase into mouse brain cells, driving functional gene recombination in multiple brain regions. PBA-Q76-O16B can be used in studies related to lipid nanoparticles (LNPs) .
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