5 Results for "

AEP Inhibitor

" in MedChemExpress (MCE) Product Catalog:
Products (5)

5 Results for "AEP Inhibitor" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-114174
CAS No.: 220701-06-4
Purity:  99.13%
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Fmoc-Ala-Glu-Asn-Lys-NH2 is a selective asparagine endopeptidase (AEP) inhibitor peptide and suppresses amyloid precursor protein (APP) cleavage. AEP, a pH-controlled cysteine proteinase, is activated during ageing and mediates APP proteolytic processing .
loading...
    loading...
Cat. No.: HY-153986
CAS No.: 2565572-83-8
Purity:  99.13%
Target:  

Cathepsin

Research Areas:  

Neurological Disease

AEP-IN-2 is an asparagine endopeptidase (AEP) inhibitor via block AEP cleavage of APP and Tau. AEP-IN-2 has oral activity and decreases Aβ40 and Aβ42 and p-Tau levels .
loading...
    loading...
Cat. No.: HY-162076
CAS No.: 2978521-26-3
Target:  

Cathepsin

Research Areas:  

Neurological Disease

AEP-IN-3 (compound 18) is an orally active, potent and brain penetrant asparagine endopeptidase (AEP) inhibitor, with an IC50 of 7.8 ± 0.9 nM. AEP-IN-3 can be used for Alzheimer’s Disease (AD) research .
loading...
    loading...
Cat. No.: HY-146068
CAS No.: 3032742-75-6
Target:  

Cathepsin

Research Areas:  

Neurological Disease

AEP-IN-1 (Compound 13e) is a CNS agent-like non-covalent inhibitor of asparagine endopeptidase (AEP), with the IC50 of 89 nM. AEP-IN-1 can be used for the research of numerous neurological diseases such as Alzheimer’s disease (AD) .
loading...
    loading...
Cat. No.: HY-133570
CAS No.: 75747-23-8
Target:  

HSP ADC Payloads

Research Areas:  

Cancer

17-AEP-GA, an HSP90 antagonist, is a potent inhibitor of glioblastoma cell proliferation, survival, migration and invasion. ADCs Toxin .
loading...
    loading...