AEP-IN-1
AEP-IN-1 (Compound 13e) is a CNS agent-like non-covalent inhibitor of asparagine endopeptidase (AEP), with the IC50 of 89 nM. AEP-IN-1 can be used for the research of numerous neurological diseases such as Alzheimer’s disease (AD).
For research use only. We do not sell to patients.
- CAS No.: 3032742-75-6
- Formula: C18H27N3O3
- Molecular Weight:333.43
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Cathepsin Isoforms
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Biological Activity
APE-IN-1 (5-500 nM; 24 hours) does not change cell viability in L929 normal fibroblasts at different concentrations[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:L929 cells
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Concentration:5, 10, 50, 100 and 500 mM
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Incubation Time:24 hours
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Result:Does not affected L929 cell viability, even at the higher doses.
Chemical Information
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CAS No. 3032742-75-6
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Molecular Weight 333.43
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Formula C18H27N3O3
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SMILES
O=C(C1CCN(C2=CC(N3CCOCC3)=CC=C2N)CC1)OCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)