6 Results for "

ASC PYD

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "ASC PYD" in MCE Product Catalog:

7
7 Publications Verification
Cat. No.: HY-P80548
Synonyms: PYCARD; ASC; CARD5; TMS1; Apoptosis-associated speck-like protein containing a CARD; hASC; Caspase recruitment domain-containing protein 5; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1

Host:  

Rabbit

Application:  

WB, IHC-F, IHC-P, ICC/IF, ELISA

Reactivity:  

Human, Mouse, Rat

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1
1 Cited Publications
Cat. No.: HY-P80522
Synonyms: PYCARD; ASC; CARD5; TMS1; Apoptosis-associated speck-like protein containing a CARD; hASC; Caspase recruitment domain-containing protein 5; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1

Host:  

Rabbit

Application:  

WB, ICC/IF, FC

Reactivity:  

Human

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1
1 Cited Publications
Cat. No.: HY-P701308
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PYCARD; PYD And CARD Domain Containing; CARD5; ASC; Apoptosis-Associated Speck-Like Protein Containing A CARD; TMS-1; Caspase Recruitment Domain-Containing Protein 5; TMS1; PYD And CARD Domain-Containing Protein; TMS; HASC
Species:  
Source:  
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Cat. No.: HY-P11581
MNP2 is a NLRP3-ASC interaction inhibitor. MNP2 selectively binds to the PYD domain of ASC (Ka=149 nM) and blocks ASC-PYM binding (Ka=58 nM), thereby inhibiting the interaction between ASC and NLRP3 and suppressing the formation of the NLRP3 inflammasome. MNP2 inhibits IL-1β release and caspase-1 maturation, and reduces the efflux of potassium and chloride ions. MNP2 prevents mitochondrial damage and reactive oxygen species production, and significantly decreases NLRP3 inflammasome formation in neurodegenerative pathologies induced by β-amyloid, Tau protein and α-synuclein. MNP2 is applicable for the research of neurodegenerative diseases .
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Cat. No.: HY-P87932
Synonyms: ASC, CARD5, TMS1, PYCARD, Apoptosis-associated speck-like protein containing a CARD, hASC, Caspase recruitment domain-containing protein 5, PYD and CARD domain-containing protein, Target of methylation-induced silencing 1

Host:  

Rabbit

Application:  

WB, IHC-P, IHC-F, ELISA

Reactivity:  

Human, Mouse

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Cat. No.: HY-P86234
Synonyms: PYCARD; ASC; CARD5; TMS1; Apoptosis-associated speck-like protein containing a CARD; hASC; Caspase recruitment domain-containing protein 5; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1

Host:  

Rabbit

Application:  

WB, ICC/IF, IP, ELISA

Reactivity:  

Mouse, Rat

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