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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
28 Results for "
Acetoacetyl-CoA
" in MedChemExpress (MCE) Product Catalog:
Products (28)
28 Results for "Acetoacetyl-CoA" in MCE Product Catalog:
Category:
Human Gut Microbiota Metabolites Metabolic Disease Endogenous metabolite Disease Research Fields
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5
5 Cited Publications
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GSK2194069 is a potent inhibitor of β-ketoyl reductase (KR) of fatty acid synthase (FASN), with an IC50 value of 7.7 nM. GSK2194069 shows specifically inhibitory effect on FAS expressing cancer cells, by acting potent efficacy on acetoacetyl-CoA, NADPH with IC50 or Ki values of 4.8 nM and 5.6 nM, respectively .
4
4 Cited Publications
Cat. No.: HY-P2161B
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1
1 Cited Publications
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Cat. No.: HY-N7392A
Synonyms: 3-Oxobutanoyl-coenzyme A sodium hydrate
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GSK837149A is a selective inhibitor of human Fatty Acid Synthase (FASN) targeting the KR domain. GSK837149A has reversible inhibition effect on FASN and selectivity for type I FASN (Ki=30 nM). GSK837149A is also a competitive inhibitor of NADPH and a non-competitive inhibitor of acetoacetyl-CoA. GSK837149A can be used for the research of obesity and breast cancer .
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Cat. No.: HY-P5544
CAS No.: 60230-21-9
Synonyms: N-Acetylmuramyl-L-Ala-γ-D-Glu-meso-diaminopimelic acid
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Cat. No.: HY-113408R
CAS No.: 64681-36-3
Cat. No.: HY-E72056
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Acetoacetyl-CoA hydrolase (EC 3.1.2.11) is a hydrolase that can convert acetoacetyl-CoA and H2O into acetoacetate, CoA and H +.
Cat. No.: HY-E72058
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Acetoacetyl-CoA synthase (EC 2.3.1.194) is a transferase that can convert malonyl-CoA, acetyl-CoA and H + into acetoacetyl-CoA, CO2 and CoA.
Cat. No.: HY-E72057
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Acetoacetyl-CoA reductase (EC 1.1.1.36) is an oxidoreductase that can convert a (3R)-3-hydroxyacyl-CoA and NADP + into a 3-oxoacyl-CoA, NADPH and H +.
Cat. No.: HY-P2161
CAS No.: 872719-49-8
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Cat. No.: HY-178918
CAS No.: 1282141-20-1
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XZA-1 is a 3-hydroxyacyl-coenzyme A dehydrogenase (HADH) activator. XZA-1 increases the intracellular level of acetoacetyl-CoA, which in turn induces acetoacetylation modification of Chromobox Protein Homolog 4 (CBX4) at lysine 106 (K106). XZA-1 exhibits antitumor effects in a xenograft model of human hepatocellular carcinoma SMMC7721 cells overexpressing CBX4. XZA-1 can be used for the study of hepatocellular carcinoma .
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Cat. No.: HY-141475
CAS No.: 102029-52-7
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Cat. No.: HY-P2115
CAS No.: 127932-90-5
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Cat. No.: HY-E72079
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Acetyl-coenzyme A acetyltransferase 2 from human (Recombinant) is a transferase that can convert 2 acetyl-CoA into acetoacetyl-CoA and CoA.
Cat. No.: HY-E72055
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Acetoacetate-CoA ligase (EC 6.2.1.16) is a ligase that can convert acetoacetate, ATP and CoA into acetoacetyl-CoA, AMP and diphosphate.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
