127932-90-5
Chemical Structure
Ramorelix
- CAS No.: 127932-90-5
- Formula:C74H95ClN16O18
- Molecular Weight:1532.10
IUPAC Name: 2-(N-((R)-2-((R)-2-acetamido-3-(naphthalen-2-yl)propanamido)-3-(4-chlorophenyl)propanoyl)-D-tryptophyl-L-seryl-L-tyrosyl-O-((2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyltetrahydro-2H-pyran-2-yl)-D-seryl-L-leucyl-L-arginyl-L-prolyl)hydrazine-1-carboxamide
InChIKey: WDYSQADGBBEGRQ-APSDYLPASA-N
SMILES: O=C(NNC(N)=O)[C@H]1N(C([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@@H](CO[C@H]2[C@@H]([C@@H]([C@H]([C@H](C)O2)O)O)O)NC([C@H](CC3=CC=C(O)C=C3)NC([C@H](CO)NC([C@@H](CC4=CNC5=C4C=CC=C5)NC([C@@H](CC6=CC=C(Cl)C=C6)NC([C@@H](CC7=CC=C8C=CC=CC8=C7)NC(C)=O)=O)=O)=O)=O)=O)=O)=O)=O)CCC1
Biological Activity: Ramorelix is a luteinizing-hormone-releasing hormone (LHRH) antagonist. Ramorelix can inhibit tumor progression in vivo. Ramorelix can be studied in anti-cancer research[1].
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Ramorelix | Ramorelix is a luteinizing-hormone-releasing hormone (LHRH) antagonist. Ramorelix can inhibit tumor progression in vivo. Ramorelix can be studied in anti-cancer research. | |||||||||||||||||||||
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References
- [1]. Stoeckemann, K., & Sandow, J. (1993). Effects of the luteinizing-hormone-releasing hormone (LHRH) antagonist ramorelix (hoe013) and the LHRH agonist buserelin on dimethylbenz[]anthracene-induced mammary carcinoma: studies with slow-release formulations. Journal of cancer research and clinical oncology, 119(8), 457-462. [Content Brief]
