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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
5 Results for "
Adipocyte hypertrophy
" in MedChemExpress (MCE) Product Catalog:
Products (5)
5 Results for "Adipocyte hypertrophy" in MCE Product Catalog:
Cat. No.: HY-W009417
CAS No.: 77-54-3
Category:
Terpenoids Sesquiterpenes Metabolic Disease Taxodiaceae Plants Cunninghamia lanceolata var. konishii Disease Research Fields
Target:
Cat. No.: HY-W012865
CAS No.: 80-69-3
Research Areas:
Tartronic acid, a dicarboxylic acid derive, is an inhibitor of the transformation of carbohydrates into fat under fat-deficient diet conditions. Tartronic acid promotes 3T3-L1 adipocyte differentiation by increasing the protein expression of FABP-4, PPARγ and SREBP-1. Tartronic acid promotes de novo lipogenesis and inhibits CPT-1β by upregulating acetyl-CoA and malonyl-CoA. Tartronic acid promotes weight gain and induces adipocyte hypertrophy in epididymal white adipose tissue and lipid accumulation in the livers of high-fat diet induced obese mice. Tartronic acid can be used for lipid metabolic disease research .
Cat. No.: HY-W109613
CAS No.: 1235-74-1
Cat. No.: HY-W009417R
CAS No.: 77-54-3
Cat. No.: HY-184895
Target:
Cryptochrome REV-ERB Nuclear Hormone Receptor 4A/NR4A FABP PARP Fatty Acid Synthase (FASN) Wnt β-catenin Hormone-Sensitive Lipase (HSL) PGC-1α ROR GLUT
Research Areas:
CM002 is a circadian clock activator. CM002 inhibits the lineage commitment and terminal differentiation of preadipocytes by activating the circadian clock, thereby blocking the adipogenesis process driven by Wnt signaling-mediated transcriptional induction. CM002 attenuates lipid storage in a clock-dependent manner via inhibition of the lipogenic program in mature adipocytes. CM002 enhances circadian clock output across various adipose depots in both lean and obese mice through BMAL1/CLOCK-dependent metabolic reprogramming, inhibits adipocyte development and hypertrophy, and improves insulin sensitivity. CM002 can be used in research on obesity and type 2 diabetes .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
