77-54-3
Chemical Structure
Cedryl acetate
- CAS No.: 77-54-3
- Formula:C17H28O2
- Molecular Weight:264.40
IUPAC Name: (3R,3aS,6R,7R,8aS)-3,6,8,8-tetramethyloctahydro-1H-3a,7-methanoazulen-6-yl acetate
InChIKey: HQKQRXZEXPXXIG-DTWJZALFSA-N
SMILES: CC1(C)[C@]2([H])[C@](C)(OC(C)=O)CC[C@]3(C2)[C@H](C)CC[C@@]13[H]
Biological Activity: Cedryl acetate is an orally active α-glucosidase inhibitor with an IC50 of 94 μM against yeast α-glucosidase. Cedryl acetate reduces high-fat diet-induced body weight gain, visceral fat pad weight, adipocyte hypertrophy, hepatic lipid accumulation, glucose intolerance, insulin resistance and gluconeogenesis. Cedryl acetate can be used in the research of obesity and obesity-related metabolic syndrome[1][2].
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Cedryl acetate | 99.43% | Cedryl acetate is an orally active α-glucosidase inhibitor with an IC50 of 94 μM against yeast α-glucosidase. Cedryl acetate reduces high-fat diet-induced body weight gain, visceral fat pad weight, adipocyte hypertrophy, hepatic lipid accumulation, glucose intolerance, insulin resistance and gluconeogenesis. Cedryl acetate can be used in the research of obesity and obesity-related metabolic syndrome. | ||||||||||||||||||||
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Cedryl acetate (Standard) | ≥98% | Cedryl acetate (Standard) is the analytical standard of Cedryl acetate. This product is intended for research and analytical applications. Cedryl acetate is an orally active α-glucosidase inhibitor with an IC50 of 94 μM against yeast α-glucosidase. Cedryl acetate reduces high-fat diet-induced body weight gain, visceral fat pad weight, adipocyte hypertrophy, hepatic lipid accumulation, glucose intolerance, insulin resistance and gluconeogenesis. Cedryl acetate can be used in the research of obesity and obesity-related metabolic syndrome. | ||||||||||||||||||||
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- [1]. Guo J, et al. Dietary Supplementation of Cedryl Acetate Ameliorates Adiposity and Improves Glucose Homeostasis in High-Fat Diet-Fed Mice. Nutrients. 2023;15(4):980. Published 2023 Feb 16. [Content Brief]
- [2]. Sultan S, et al. Fungal transformation of cedryl acetate and α-glucosidase inhibition assay, quantum mechanical calculations and molecular docking studies of its metabolites. Eur J Med Chem. 2013;62:764-770. [Content Brief]
