Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
6 Results for "
Agelas
" in MedChemExpress (MCE) Product Catalog:
Products (6)
6 Results for "Agelas" in MCE Product Catalog:
Cat. No.: HY-123888
CAS No.: 55625-78-0
Category:
Target:
Cat. No.: HY-125132
CAS No.: 152406-28-5
Synonyms: (-)-Agelastatin A; AglA
Category:
Target:
Cat. No.: HY-113621B
CAS No.: 2757574-06-2
Target:
Research Areas:
Ageladine A dihydrochloride is an inhibitor of matrix metalloproteinase (MMP) isolated from the marine sponge Agelas nakamurai, possessing anti-angiogenic activity. Ageladine A dihydrochloride not only inhibits MMP-2 but also MMP-1, MMP-8, MMP-9, MMP-12, and MMP-13, with IC50 values of 4.65 μM, 2.79 μM, 907.12 nM, 1.83 μM, 767.57 nM, and 1.09 μM, respectively. Additionally, Ageladine A dihydrochloride is a pH-sensitive membrane-permeable dye that emits fluorescence in the blue-green range upon UV excitation, featuring a maximum absorption peak at 370 nm. Furthermore, Ageladine A dihydrochloride serves as a reliable and stable fluorescent pH sensor for detecting changes in intracellular pH values .
Cat. No.: HY-N7747
CAS No.: 79703-25-6
Category:
Target:
Cat. No.: HY-116436
CAS No.: 135383-64-1
Target:
Research Areas:
Clathrodin is a marine alkaloid that can be isolated from sponges of the genus, Agelas. Clathrodin is a modulator of voltage-gated sodium (NaV) channels. Clathrodin is a sodium channel neurotoxin influencing sodium channel ionic conductance .
Cat. No.: HY-N1662
CAS No.: 203524-64-5
Category:
Alkaloids Animals Marine natural products Other Diseases Pyridine Alkaloids Sponge Disease Research Fields
Target:
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
