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Asciminib

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-104010
    Asciminib
    10+ Cited Publications

    ABL001

    		 Bcr-Abl Cancer
    Asciminib (ABL001) is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM .
    Asciminib
  • HY-104010A
    Asciminib hydrochloride
    10+ Cited Publications

    ABL001 hydrochloride

    		 Bcr-Abl Cancer
    Asciminib (ABL001) hydrochloride is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM .
    Asciminib hydrochloride
  • HY-104010R
    Asciminib (Standard)

    ABL001 (Standard)

    		 Reference Standards Bcr-Abl Cancer
    Asciminib (Standard) is the analytical standard of Asciminib. This product is intended for research and analytical applications. Asciminib (ABL001) is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM .
    Asciminib (Standard)
  • HY-104010AR
    Asciminib hydrochloride (Standard)

    ABL001 hydrochloride (Standard)

    		 Reference Standards Bcr-Abl Cancer
    Asciminib hydrochloride (Standard) is the analytical standard of Asciminib hydrochloride (HY-104010A). This product is intended for research and analytical applications. Asciminib (ABL001) hydrochloride is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM .
    Asciminib hydrochloride (Standard)
  • HY-180982
    Asciminib-NH2

    		Target Protein Ligand-Linker Conjugates Bcr-Abl Cancer
    Asciminib-NH2 is a BCR-ABL ligand and can be used for the synthesis of PROTACs, such as P19As (HY-180981) .
    Asciminib-NH2
  • HY-180981
    P19As

    		PROTACs Bcr-Abl Cancer
    P19As is a BCR-ABL PROTAC degrader based on Asciminib (HY-104010), with a DC50 value of approximately 200 nM for the wild-type BCR-ABL protein. P19As can degrade the T315I mutant and exhibits potent anti-proliferative activity in BaF3-BCR-ABL (T315I) cells. P19As can be used for the study of chronic myeloid leukemia and acute lymphoblastic leukemia .
    P19As

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