2119669-71-3
2119669-71-3
Chemical Structure
Asciminib hydrochloride
Synonym(s): ABL001 hydrochloride
- CAS No.: 2119669-71-3
- Formula:C20H19Cl2F2N5O3
- Molecular Weight:486.30
IUPAC Name: (R)-N-(4-(chlorodifluoromethoxy)phenyl)-6-(3-hydroxypyrrolidin-1-yl)-5-(1H-pyrazol-3-yl)nicotinamide hydrochloride
InChIKey: HGCOOPLEWPBLOY-PFEQFJNWSA-N
SMILES: O=C(NC1=CC=C(C=C1)OC(Cl)(F)F)C2=CC(C3=NNC=C3)=C(N=C2)N4C[C@@H](CC4)O.[H]Cl
Biological Activity: Asciminib (ABL001) hydrochloride is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM[1].
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Asciminib hydrochloride | 99.79% | Asciminib (ABL001) hydrochloride is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM. | ||||||||||||||||||||
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Asciminib hydrochloride (Standard) | ≥98% | Asciminib hydrochloride (Standard) is the analytical standard of Asciminib hydrochloride (HY-104010A). This product is intended for research and analytical applications. Asciminib (ABL001) hydrochloride is a potent and selective allosteric BCR-ABL1 inhibitor, which inhibits Ba/F3 cells grown with an IC50 of 0.25 nM. | ||||||||||||||||||||
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References
