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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
10 Results for "
BPP
" in MedChemExpress (MCE) Product Catalog:
Products (10)
10 Results for "BPP" in MCE Product Catalog:
Art. -Nr.: HY-121426
CAS. Nr.: 73671-44-0
3
3 Cited Publications
Target:
Forschungsgebiete:
Raphin1 is an orally bioavailable, selective inhibitor of the regulatory phosphatase PPP1R15B (R15B). Raphin1 binds strongly to the R15B-PP1c holophosphatase (Kd=33 nM), and shows ~30-fold selective in binding R15B-PP1c over R15A-PP1c. Raphin1 crosses the blood-brain barrier, and reduces organismal and molecular deficits in a mouse model of a protein misfolding disease .
3
3 Cited Publications
Target:
Forschungsgebiete:
Raphin1 acetate is an orally bioavailable, selective inhibitor of the regulatory phosphatase PPP1R15B (R15B). Raphin1 acetate binds strongly to the R15B-PP1c holophosphatase (Kd=33 nM), and shows ~30-fold selective in binding R15B-PP1c over R15A-PP1c. Raphin1 acetate crosses the blood-brain barrier, and reduces organismal and molecular deficits in a mouse model of a protein misfolding disease .
Art. -Nr.: HY-W009062
CAS. Nr.: 251320-86-2
Art. -Nr.: HY-P2619
CAS. Nr.: 30505-63-6
Forschungsgebiete:
Art. -Nr.: HY-W023758
CAS. Nr.: 166196-54-9
Synonyms: 4-(4-Bromo-1H-pyrazol-5-yl)pyridine
Target:
Forschungsgebiete:
HDGFRP2/PSIP1-IN-1 (compound BPP) is a dual inhibitor targeting the PWWP domain of hepatocarcinogenic growth factor-related protein 2 (HDGFRP2) and its homologous protein PSIP1, hinder the development and progression of diffuse intrinsic pontine glioma (DIPG). HDGFRP2/PSIP1-IN-1 binds to HDGFRP2 with a Kd value of 7 μM and a ligand efficiency of 0.47; it binds to the PSIP1 PWWP domain with a Kd value of 27 μM; meanwhile, it has a Kd value of 14 μM for HDGFRP3, indicating its effectiveness as an inhibitor of the HDGFRP2 PWWP subfamily .
Art. -Nr.: HY-RS13783
Target:
Forschungsgebiete:
SRPX2 Human Pre-designed siRNA Set A contains three designed siRNAs for SRPX2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-P71594
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SRPX2; Sushi-Repeat-Containing Protein, X-Linked 2; Sushi Repeat Containing Protein X-Linked 2; RESDX; SRPUL; CBPS; Sushi Repeat-Containing Protein SRPX2; PMGX; Sushi-Repeat Protein Upregulated In Leukemia; BPP; Sushi-Repeat Protein Up-Regulated In Leukem
Art. -Nr.: HY-P706006
Reinheit: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SRPX2; Sushi-Repeat-Containing Protein, X-Linked 2; Sushi Repeat Containing Protein X-Linked 2; RESDX; SRPUL; CBPS; Sushi Repeat-Containing Protein SRPX2; PMGX; Sushi-Repeat Protein Upregulated In Leukemia; BPP; Sushi-Repeat Protein Up-Regulated In Leukem
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
