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SRPX2 Protein, Mouse (Myc, His-SUMO)

Cat. No.: HY-P71594
Handling Instructions

SRPX2 Protein, a ligand for the urokinase plasminogen activator surface receptor, promotes angiogenesis by inducing endothelial cell migration and vascular network formation. It also crucially influences cellular migration and adhesion, increasing FAK phosphorylation and enhancing HGF mitogenic activity. SRPX2 participates in synapse formation and is vital for ultrasonic vocalizations. The protein forms homooligomers and interacts with PLAUR, ADAMTS4, and CTSB, highlighting its diverse roles in cellular processes and signaling pathways. SRPX2 Protein, Mouse (Myc, His-SUMO) is the recombinant mouse-derived SRPX2 protein, expressed by E. coli, with N-His, C-Myc, N-SUMO labeled tag. The total length of SRPX2 Protein, Mouse (Myc, His-SUMO) is 443 a.a., with molecular weight of ~70.5 kDa.

For research use only. We do not sell to patients.

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Description

SRPX2 Protein, a ligand for the urokinase plasminogen activator surface receptor, promotes angiogenesis by inducing endothelial cell migration and vascular network formation. It also crucially influences cellular migration and adhesion, increasing FAK phosphorylation and enhancing HGF mitogenic activity. SRPX2 participates in synapse formation and is vital for ultrasonic vocalizations. The protein forms homooligomers and interacts with PLAUR, ADAMTS4, and CTSB, highlighting its diverse roles in cellular processes and signaling pathways. SRPX2 Protein, Mouse (Myc, His-SUMO) is the recombinant mouse-derived SRPX2 protein, expressed by E. coli, with N-His, C-Myc, N-SUMO labeled tag. The total length of SRPX2 Protein, Mouse (Myc, His-SUMO) is 443 a.a., with molecular weight of ~70.5 kDa.

Background

SRPX2 Protein serves as a ligand for the urokinase plasminogen activator surface receptor, contributing to angiogenesis by inducing endothelial cell migration and the formation of vascular networks. Additionally, it plays a crucial role in cellular migration and adhesion, elevates phosphorylation levels of FAK (focal adhesion kinase), and interacts with and enhances the mitogenic activity of HGF (hepatocyte growth factor). SRPX2 also participates in synapse formation and is essential for ultrasonic vocalizations. It forms homooligomers and interacts with PLAUR, ADAMTS4, and CTSB, further emphasizing its multifaceted roles in cellular processes and signaling pathways.

Species

Mouse

Source

E. coli

Tag

N-His;C-Myc;N-SUMO

Accession

Q8R054 (26W-468E)

Gene ID

68792  [NCBI]

Molecular Construction
N-term
10*His-SUMO
SRPX2 (26W-468E)
Accession # Q8R054
C-term
Synonyms
Srpx2; Sushi repeat-containing protein SRPX2
AA Sequence

WYAGSGYSPDESYNEVYAEEVPAARARALDYRVPRWCYTLNIQDGEATCYSPRGGNYHSSLGTRCELSCDRGFRLIGRKSVQCLPSRRWSGTAYCRQIRCHTLPFITSGTYTCTNGMLLDSRCDYSCSSGYHLEGDRSRICMEDGRWSGGEPVCVDIDPPKIRCPHSREKMAEPEKLTARVYWDPPLVKDSADGTITRVTLRGPEPGSHFPEGEHVIRYTAYDRAYNRASCKFIVKVQVRRCPILKPPQHGYLTCSSAGDNYGAICEYHCDGGYERQGTPSRVCQSSRQWSGTPPVCTPMKINVNVNSAAGLLDQFYEKQRLLIVSAPDPSNRYYKMQISMLQQSTCGLDLRHVTIIELVGQPPQEVGRIREQQLSAGIIEELRQFQRLTRSYFNMVLIDKQGIDRERYMEPVTPEEIFTFIDDYLLSNEELARRVEQRDLCE

Molecular Weight

Approximately 70.5 kDa

Purity

Greater than 90% as determined by reducing SDS-PAGE.

Endotoxin Level

<1 EU/μg, determined by LAL method.

Documentation

SRPX2 Protein, Mouse (Myc, His-SUMO) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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SRPX2 Protein, Mouse (Myc, His-SUMO)
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HY-P71594
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