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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
BSS-Et
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "BSS-Et" in MCE Product Catalog:
Cat. No.: HY-184451
CAS No.: 2825003-94-7
Research Areas:
BSS-Et is a near-infrared phototheranostic agent that serves as one of the two release units of hypoxia-responsive prodrug BNNC, responsible for generating photodynamic therapy (PDT) and photothermal therapy (PTT) effects at tumor sites. BSS-Et produces reactive oxygen species and singlet oxygen upon irradiation, inducing oxidative stress and DNA damage. When combined with (R)-CR8 (HY-18340), BSS-Et enhances DNA damage and apoptosis in breast cancer cells. BSS-Et can be used in breast cancer-related research .
Cat. No.: HY-184452
Research Areas:
BNNC is a Photomolecular glue . BNNC selectively releases (R)-CR8 (HY-18340) (a Cyclin K molecular glue) and BSS-Et in hypoxic tumor microenvironments, thereby triggering Cyclin K degradation dependent on the ubiquitin-proteasome pathway. BNNC generates ROS and singlet oxygen in hypoxic tumor cells under light irradiation. BNNC enhances DNA damage and Apoptosis through the combined effects of Cyclin K degradation and phototherapy. BNNC enhances the tumor selectivity of molecular glue via specific activation in hypoxic tumor microenvironments. BNNC can be used in breast cancer-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
