2825003-94-7
Chemical Structure
BSS-Et
- No. CAS: 2825003-94-7
- Formula:C33H31ClN4O3
- Molecular Weight:567.08
InChIKey: CQUKITSUXAOPME-UNTXXVRYSA-N
SMILES: CC(O/1)(C)C(/C=C/C(CCC/2)=C(Cl)C2=C\C=C3C(C)(C)C(C=C(C(O)=O)C=C4)=C4N\3CC)=C(C#N)C1=C(C#N)\C#N
Biological Activity: BSS-Et is a near-infrared phototheranostic agent that serves as one of the two release units of hypoxia-responsive prodrug BNNC, responsible for generating photodynamic therapy (PDT) and photothermal therapy (PTT) effects at tumor sites. BSS-Et produces reactive oxygen species and singlet oxygen upon irradiation, inducing oxidative stress and DNA damage. When combined with (R)-CR8 (HY-18340), BSS-Et enhances DNA damage and apoptosis in breast cancer cells. BSS-Et can be used in breast cancer-related research[1].
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BSS-Et | BSS-Et is a near-infrared phototheranostic agent that serves as one of the two release units of hypoxia-responsive prodrug BNNC, responsible for generating photodynamic therapy (PDT) and photothermal therapy (PTT) effects at tumor sites. BSS-Et produces reactive oxygen species and singlet oxygen upon irradiation, inducing oxidative stress and DNA damage. When combined with (R)-CR8 (HY-18340), BSS-Et enhances DNA damage and apoptosis in breast cancer cells. BSS-Et can be used in breast cancer-related research. | |||||||||||||||||||||
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