2 Results for "

Bellidifolin

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Bellidifolin" in MCE Product Catalog:

2
Bellidifolin
Bellidifolin
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2 Cited Publications
Cat. No.: HY-N2000
CAS No.: 2798-25-6
Category:  

Infection Xanthones Gentianaceae Swertia bimaculata (Sieb. et Zucc.) Hook. f. et Thoms. ex C. B. Clark Phenols Polyphenols Plants Disease Research Fields Inflammation/Immunology

Target:  

STAT PI3K mTOR Akt

Bellidifolin is an orally active compound with antiproliferative, anti-inflammatory and antioxidant properties. Bellidifolin modulates key signaling pathways including STAT3, PI3K-Akt, mTOR and BRD4, and inhibits the viral protein R (Vpr). Bellidifolin induces cell cycle arrest and apoptosis, exerts significant antifibrotic effects, and protects the heart, liver and nervous system. Bellidifolin is applicable to the research of various diseases such as lung cancer, non-alcoholic fatty liver disease, myocardial hypertrophy and ischemic cranial nerve injury .
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Tetrahydro bellidifolin
Tetrahydro bellidifolin
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Cat. No.: HY-N18019
CAS No.: 189289-77-8
Category:  

Xanthones Gentianaceae Swertia bimaculata (Sieb. et Zucc.) Hook. f. et Thoms. ex C. B. Clark Phenols Plants

Target:  

Drug Metabolite

Tetrahydro bellidifolin (Compound 1a) is the aglycone obtained from the hydrolysis of Tetrahydroswertianolin (HY-N18018) by β-glucosidase. Tetrahydro bellidifolin exhibits significant hepatoprotective activity and reduce serum ALT levels. Tetrahydro bellidifolin can be used for the research of liver injury .
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