1 Result for "

Berkeleyacetal C

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Berkeleyacetal C" in MCE Product Catalog:

Berkeleyacetal C
Berkeleyacetal C
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Cat. No.: HY-N10175
CAS No.: 959772-67-9
Category:  

Other Terpenoids Human Gut Microbiota Metabolites Microorganisms Terpenoids Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

NO Synthase NF-κB ERK Interleukin Related TNF Receptor Reactive Oxygen Species (ROS)

keleyacetal C, a meroterpenoid compound with anti-inflammatory effects via inhibiting NF-κB, ERK1/2 and IRF3 signaling pathways. Berkeleyacetal C significantly inhibits the expression of iNOS and the following NO production by macrophages. Berkeleyacetal C inhibits expression and secretion of key pro-inflammatory factors and chemokines (TNF-α, IL-6, IL-1β, MIP-1α, and MCP-1). Berkeleyacetal C also inhibits activation of neutrophils and reactive oxygen species (ROS) production. Berkeleyacetal C can be used for the study of inflammatory disorders .
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