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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
17 Results for "
CHEK1
" in MedChemExpress (MCE) Product Catalog:
Products (17)
17 Results for "CHEK1" in MCE Product Catalog:
2
1
Research Areas:
Neurological Disease Metabolic Disease Inflammation/Immunology Cancer
FMF-06-098-1 is a multi-target kinase PROTAC degrader. FMF-06-098-1 can be used to target degradation kinases which degrades AAK1, AΒL2, AURKA, AURKB, BUBIB, CDC7, CDK1, CDK12, CDK13, CDK2, CDK4, CDk6, CDK7, CDK9, CHEK1, CSNKID, EPHA1, PER, FGFR1, GAK, IRAK4, ITK, LIMK2, MAP4K2, MAP4K3, MAPK6, MAPK7, MARK4, MELK, PKN3, PLK4, PRKAA1, PTK2, PTK6, RPS6KA4, S1K2, STK35, TNK2, UHMK1, ULK1, and WEE1 [1].
Cat. No.: HY-RS02616
Research Areas:
CHEK1 Human Pre-designed siRNA Set A contains three designed siRNAs for CHEK1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02617
Research Areas:
Chek1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Chek1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS02618
Research Areas:
Chek1 Rat Pre-designed siRNA Set A contains three designed siRNAs for Chek1 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-173147
CDK2-IN-42 (Compound H63) is a CDK12 inhibitor with an IC50 value of 10 nM. CDK2-IN-42 has anti-ESCC (Esophageal Squamous Cell Carcinoma) cell activity. It can block transcriptional elongation, downregulate the core genes in the G1 phase to induce cell cycle arrest, and alter the CDK12-ATM/ATR-CHEK1/CHEK2 signaling axis, resulting in DNA damage. CDK2-IN-42 can effectively inhibit tumor growth in a xenograft mouse model of human ESCC KYSE150. CDK2-IN-42 holds great promise for research in the field of cancer [1].
Cat. No.: HY-N15249
CAS No.: 267662-22-6
Synonyms: Isovalerylspiramycin I; Shengjimycin E
Category:
Cat. No.: HY-P75672
Purity: ≥ 85%, as determined by reducing SDS-PAGE.
Synonyms: CHEK1; Non-Specific Serine/Threonine Protein Kinase; Checkpoint Kinase 1; Checkpoint, S. Pombe, Homolog Of, 1; CHK1; CHK1 (Checkpoint, S.Pombe) Homolog; Serine/Threonine-Protein Kinase Chk1; CHK1 Checkpoint Homolog (S. Pombe); CHK1 Checkpoint Homolog; OZE
Species:
Source:
Cat. No.: HY-P74253
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CHEK1; Non-Specific Serine/Threonine Protein Kinase; Checkpoint Kinase 1; Checkpoint, S. Pombe, Homolog Of, 1; CHK1; CHK1 (Checkpoint, S.Pombe) Homolog; Serine/Threonine-Protein Kinase Chk1; CHK1 Checkpoint Homolog (S. Pombe); CHK1 Checkpoint Homolog; OZE
Species:
Source:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
