29 Results for "

Cardiolipin

" in MedChemExpress (MCE) Product Catalog:
Products (29)

29 Results for "Cardiolipin" in MCE Product Catalog:

5
5 Cited Publications
Cat. No.: HY-125623
CAS No.: 1392820-50-6
Purity:  98.14%
MitoPerOx is a mitochondrial-targeted, lipid peroxidation-indicating fluorescent probe with BODIPY581/591 fluorophores. The triphenylphosphine cation (TPP+) of MitoPerOx can be selectively enriched in mitochondria (depending on membrane potential) and can be used to detect lipid peroxidation in the inner mitochondrial membrane. Under the action of lipid peroxides, the BODIPY581/591 fluorophores of MitoPerOx shift their emission wavelength from 590 nm (reduced state) to 520 nm (oxidized state), and ratiometric detection can be performed at an excitation wavelength of 488 nm. MitoPerOx can specifically monitor the peroxidation of mitochondrial phospholipids (especially cardiolipin) and is used in the study of oxidative stress-related diseases (such as aging, neurodegenerative diseases, and mitochondrial dysfunction)[1][2].
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4
4 Cited Publications
Cat. No.: HY-D0993
CAS No.: 75168-11-5
Synonyms: Nonylacridine orange
Acridine Orange 10-Nonyl Bromide is a fluorescent probe for cardiolipinex: 489 nm, λem: 525 nm).
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3
3 Cited Publications
Cat. No.: HY-W013100
CAS No.: 36051-68-0
Synonyms: Cytidine triphosphate disodium; 5'-CTP disodium
Cytidine-5'-triphosphate (Cytidine triphosphate; 5'-CTP) disodium is a nucleoside triphosphate, that is invovled in biosynthesis of DNA, RNA and lipid. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate disodium is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii .
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2
2 Cited Publications
Cat. No.: HY-125857
CAS No.: 9007-43-6
Purity:  99.9%
Cytochrome C is a multi-functional enzyme involving in life and death decisions of the cell. Cytochrome C is essential in mitochondrial electron transport and intrinsic type II apoptosis .
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1
1 Cited Publications
Cat. No.: HY-134238
CAS No.: 383907-10-6
Purity:  ≥99.0%
Cardiolipin (Heart, Bovine) sodium is a mitochondria-exclusive phospholipid that can be extracted from Bovine hear. Cardiolipin (Heart, Bovine) sodium can maintain mitochondrial function, regulate cellular metabolism and signaling and induce apoptosis and autophagy. Cardiolipin (Heart, Bovine) sodium can be coated on microtitre plates for ELISA assay. Cardiolipin (Heart, Bovine) sodium can be used for the researches of inflammation, immunology, cardiovascular and neurological disease .
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1
1 Cited Publications
Cat. No.: HY-160202
CAS No.: 115404-77-8
Target:  

Bacterial

Research Areas:  

Infection

18:1 Cardiolipin disodium is a virulence regulator with two phosphate groups and four acyl chains.18:1 Cardiolipin disodium can be used in the study of the regulation and mechanism of bacterial infection .
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Cat. No.: HY-W018587
CAS No.: 26040-51-7
TBPH is a brominated flame retardant. TBPH enhances hepatic steatosis, inflammation, and fibrosis in mice with nonalcoholic steatohepatitis (NASH). TBPH induces dysregulation of phospholipid metabolism, reducing cardiolipin (CL) and phosphatidylserine (PS) levels. TBPH leads to impaired endoplasmic reticulum-mitochondria (ER-Mito) contacts, subsequently causing mitochondrial dysfunction. TBPH induces lung injury through an inflammatory response mediated by mitochondria-derived ds-DNA. TBPH can be used to study the role of MFN2-mediated ER-mitochondria contacts in lipid metabolism homeostasis .
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Cat. No.: HY-148009
CAS No.: 2260669-35-8
Synonyms: 16:0-18:1 Cardiolipin sodium
Research Areas:  

Others

Cardiolipin (16:0/18:1/16:0/18:1) (16:0-18:1 Cardiolipin) sodium is a di-saturated mitochondrial-specific anionic phospholipid sodium salt containing the long-chain fatty acid palmitic acid (HY-N0830) and the monounsaturated fatty acid oleic acid (HY-N1446). Cardiolipin (16:0/18:1/16:0/18:1) sodium undergoes in-source fragmentation via diglyceride (DG)-H2O fragment formation and (DG-H2O) fragment loss pathways. Cardiolipin (16:0/18:1/16:0/18:1) sodium can be used in the synthesis of lipid nanodiscs for application in in situ mass spectrometry .
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Cat. No.: HY-DY1073
CAS No.: 1392820-50-6
MitoPerOx (solution) is a mitochondrial-targeted, lipid peroxidation-indicating fluorescent probe with BODIPY581/591 fluorophores. The triphenylphosphine cation (TPP+) of MitoPerOx can be selectively enriched in mitochondria (depending on membrane potential) and can be used to detect lipid peroxidation in the inner mitochondrial membrane. Under the action of lipid peroxides, the BODIPY581/591 fluorophores of MitoPerOx shift their emission wavelength from 590 nm (reduced state) to 520 nm (oxidized state) , and ratiometric detection can be performed at an excitation wavelength of 488 nm. MitoPerOx can specifically monitor the peroxidation of mitochondrial phospholipids (especially cardiolipin) and is used in the study of oxidative stress-related diseases (such as aging, neurodegenerative diseases, and mitochondrial dysfunction) .
Solvent and concentration: DMSO: 2 mM
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Cat. No.: HY-174940
CAS No.: 1240502-50-4
E. coli Extract Polar is a polar lipid extract of Escherichia coli containing phosphatidylethanolamine, phosphatidylglycerol, and cardiolipin for reconstitution of membrane proteins.
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Cat. No.: HY-DY1078
CAS No.: 75168-11-5
Acridine Orange 10-Nonyl Bromide (solution) is a fluorescent probe for cardiolipinex: 489 nm, λem: 525 nm).
Solvent and concentration: DMSO: 10 mM
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Cat. No.: HY-116447
CAS No.: 1611446-66-2
Purity:  ≥99.0%
Research Areas:  

Cancer

Antitumor agent-159 (Compound 13b) targets the mitochondria and downregulates cardiolipin levels. Antitumor agent-159 inhibits the proliferation of cancer cell MDA-MB-231, arrests the cell cycle at sub-G1 phase, and induces apoptosis in MDA-MB-231. Antitumor agent-159 exhibits antitumor efficacy in MDA-MB-231 xenograft mouse models .
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Cat. No.: HY-130323
CAS No.: 67597-26-6
Target:  

Bacterial

Research Areas:  

Infection

13-HPOT is a linolenic acid hydroperoxide and an antibacterial agent. 13-HPOT interacts with lipid representatives of bacterial inner membranes. 13-HPOT exerts dose-dependent in vitro antibacterial activity against Pectobacterium carotovorum, Pseudomonas syringae pv. syringae DC3000, and Xanthomonas translucens pv. translucens .
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Cat. No.: HY-157661
CAS No.: 63988-21-6
Synonyms: 1',3'-Bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol sodium
14:0 Cardiolipin sodium (1',3'-Bis[1,2-dimyristoyl-sn-glycero-3-phospho]-glycerol (sodium)) is a kind of biochemical reagent.
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Cat. No.: HY-168798
CAS No.: 2260669-33-6
Target:  

Others

Research Areas:  

Metabolic Disease

14:1 Cardiolipin sodium is an anionic phospholipid containing the monounsaturated fatty acid Myristoleic acid (HY-113332).
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Cat. No.: HY-159856
CAS No.: 105380-95-8
Synonyms: Diphosphatidylglycerol (16:0)
Target:  

Liposome

Research Areas:  

Others

16:0 Cardiolipin (Diphosphatidylglycerol (16:0)) is a phospholipid derived from Palmitic acid (16:0) that can be used to synthesize lipid nanoparticles (LNP) for delivering mRNA and other payloads .
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Cat. No.: HY-W590676
CAS No.: 63988-20-5
Synonyms: TMCL diammonium
Target:  

Liposome

Research Areas:  

Others

Tetramyristoylcardiolipin (TMCL) is an anionic lipid. Tetramyristoylcardiolipin can be used to study cell membrane function and drug delivery .
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Cat. No.: HY-P2807J
CAS No.: 9001-60-9
Synonyms: L-LDH, L-LDH (pig muscle)
Target:  

Lactate Dehydrogenase

Research Areas:  

Metabolic Disease

L-Lactate Dehydrogenase (L-LDH), pig muscle is an L-lactate dehydrogenase found in pig muscle, mainly present in anaerobic tissues (skeletal muscle, red blood cells). L-Lactate Dehydrogenase (L-LDH), pig muscle can interact with acidic liposomes at low pH, causing protein to adsorb onto the liposomes and inhibit enzyme activity. The IC50 values for L-Lactate Dehydrogenase (L-LDH), pig muscle are 0.05 μM for cardiolipin and 1.3 μM for phosphatidylserine liposomes .
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Cat. No.: HY-157657
CAS No.: 2260669-34-7
Synonyms: Diphosphatidylglycerol sodium salt; 16:1 Cardiolipin sodium salt; 64:4-CL sodium salt
Target:  

Liposome

Research Areas:  

Others

Cardiolipin (16:1/16:1/16:1/16:1) sodium salt is an anionic phospholipid that promote hydroxyapatite crystallization and supersaturation in a calcium solution .
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18:0 Cardiolipin
0 Images
Octadecanoic acid, 5,8,11-trihydroxy-5,11-dioxido-4,6,10,12-tetraoxa-5,11-diphosphapentadecane-1,2,14,15-tetrayl ester, disodium salt, [R-(R*,R*)]-
Cat. No.: HY-160203
CAS No.: 64069-64-3
18:0 Cardiolipin (CL) is a polyglycerophospholipid synthesized in mitochondria, playing a crucial role in mitochondrial bioenergetics and signaling. Exclusively found in the inner mitochondrial membrane of eukaryotes, 18:0 CL exhibits a complex structure characterized by its unique chain length and degree of saturation, along with the specific arrangements of its four fatty acid substituents.
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