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Carvacrol

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By Targets:	Apoptosis (2) Bacterial (5) Biochemical Assay Reagents (1) Endogenous Metabolite (2) Environmental Pollutants (2) Fungal (2) Interleukin Related (1) Keap1-Nrf2 (1) Notch (2) PPAR (1) Reference Standards (2)
By Research Areas:	Cancer (3) Cardiovascular Disease (1) Infection (5) Inflammation/Immunology (4) Metabolic Disease (1) Neurological Disease (1)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0711

*Carvacrol* 5+ Cited Publications Cymophenol	Environmental Pollutants Apoptosis Endogenous Metabolite Notch Fungal Bacterial	Infection Neurological Disease Inflammation/Immunology Cancer
Carvacrol is an orally active and blood-brain barrier-permeable monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations .

HY-W049970

Carvacrol methyl ether	Environmental Pollutants Bacterial	Infection
Carvacrol methyl ether is a carvacrol derivative isolated from plant essential oils. Carvacrol methyl ether essentially lost its antibacterial activity, exhibiting only a weak inhibitory effect on Saccharomyces cerevisiae at the highest tested concentration of 3 g/L .

HY-175005

CF-Carvacrol	Keap1-Nrf2 PPAR Interleukin Related	Metabolic Disease Inflammation/Immunology
CF-Carvacrol is an orally active lipid-lowering agent synthesized by merging the pharmacophores of Carvacrol (HY-N0711) and Clofibric acid (HY-B1415). CF-Carvacrol has a good affinity for PPAR-α. CF-Carvacrol has significant hypolipidemic activity and may exert antioxidant and anti-inflammatory activity by activating the Nrf2/HO-1 signaling pathway to reduce liver injury. CF-Carvacrol can be used for the study of CF-induced liver damage .

HY-N0711R

Carvacrol (Standard) Cymophenol (Standard)	Reference Standards Notch Apoptosis Fungal Endogenous Metabolite Bacterial	Infection Inflammation/Immunology Cancer
Carvacrol (Standard) is the analytical standard of Carvacrol. This product is intended for research and analytical applications. Carvacrol is an orally active and blood-brain barrier-permeable monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations .

HY-W049970R

Carvacrol methyl ether (Standard)	Reference Standards Bacterial	Infection
Carvacrol methyl ether (Standard) is the analytical standard of Carvacrol methyl ether (HY-W049970). This product is intended for research and analytical applications. Carvacrol methyl ether is a carvacrol derivative isolated from plant essential oils. Carvacrol methyl ether essentially lost its antibacterial activity, exhibiting only a weak inhibitory effect on Saccharomyces cerevisiae at the highest tested concentration of 3 g/L .

HY-W127485

cis-9,10-Methyleneoctadecanoic Acid	Biochemical Assay Reagents	Others
cis-9,10-Methyleneoctadecanoic acid is a cyclopropane fatty acid that has been found in bacteria and in the digestive glands of P. globosa. It is a component of the cell membrane of Staphylococcus aureus, and levels were reduced after treatment with carvacrol. cis-9,10-Methyleneoctadecanoic acid is secreted by H. pylori and enhances histamine- and dibutyryl cAMP-stimulated acid secretion in isolated guinea pig parietal cells. It also activates protein kinase C (PKC) in a calcium-dependent manner.

HY-168120

Carvacrol-C4-3-hydroxybenzoic acid	Others	Cardiovascular Disease
Carvacrol-C4-3-hydroxybenzoic acid (compund 6) has significant cardioprotective activity and good computational ADMET properties.

HY-N18678

Origanum vulgare extract	Bacterial	Infection Inflammation/Immunology Cancer
Origanum vulgare extract is highly regarded for its rich content of various bioactive compounds, including carvacrol, thymol, rosmarinic acid, and other phenolic compounds, which have antioxidant, antibacterial, anti-inflammatory, and anticancer effects.

Cat. No.	Product Name	Type

HY-W127485

cis-9,10-Methyleneoctadecanoic Acid	Biochemical Assay Reagents
cis-9,10-Methyleneoctadecanoic acid is a cyclopropane fatty acid that has been found in bacteria and in the digestive glands of P. globosa. It is a component of the cell membrane of Staphylococcus aureus, and levels were reduced after treatment with carvacrol. cis-9,10-Methyleneoctadecanoic acid is secreted by H. pylori and enhances histamine- and dibutyryl cAMP-stimulated acid secretion in isolated guinea pig parietal cells. It also activates protein kinase C (PKC) in a calcium-dependent manner.

cis-9,10-Methyleneoctadecanoic Acid

Biochemical Assay Reagents

cis-9,10-Methyleneoctadecanoic acid is a cyclopropane fatty acid that has been found in bacteria and in the digestive glands of P. globosa. It is a component of the cell membrane of Staphylococcus aureus, and levels were reduced after treatment with carvacrol. cis-9,10-Methyleneoctadecanoic acid is secreted by H. pylori and enhances histamine- and dibutyryl cAMP-stimulated acid secretion in isolated guinea pig parietal cells. It also activates protein kinase C (PKC) in a calcium-dependent manner.

*Carvacrol* 5+ Cited Publications Cymophenol	Structural Classification Monophenols Preservatives Classification of Application Fields Labiatae Phenols Derris elliptica (Roxb.) Benth. Plants Inflammation/Immunology Disease Research Fields Food Research	Environmental Pollutants Apoptosis Endogenous Metabolite Notch Fungal Bacterial
Carvacrol is an orally active and blood-brain barrier-permeable monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations .

Carvacrol methyl ether	Infection Structural Classification Natural Products other families Classification of Application Fields Plants Disease Research Fields Source Classification	Environmental Pollutants Bacterial
Carvacrol methyl ether is a carvacrol derivative isolated from plant essential oils. Carvacrol methyl ether essentially lost its antibacterial activity, exhibiting only a weak inhibitory effect on Saccharomyces cerevisiae at the highest tested concentration of 3 g/L .

Carvacrol (Standard) Cymophenol (Standard)	Structural Classification Monophenols Labiatae Phenols Derris elliptica (Roxb.) Benth. Plants	Reference Standards Notch Apoptosis Fungal Endogenous Metabolite Bacterial
Carvacrol (Standard) is the analytical standard of Carvacrol. This product is intended for research and analytical applications. Carvacrol is an orally active and blood-brain barrier-permeable monoterpenic phenol that can be extract from an abundant number of aromatic plants, including thyme and oregano, possessing antioxidant, antibacterial, antifungal, anticancer, anti-inflammatory, hepatoprotective, spasmolytic, and vasorelaxant properties. Carvacrol also causes cell cycle arrest in G0/G1, downregulates Notch-1, and Jagged-1, and induces apoptosis. Carvacrol is used in low concentrations as a food flavoring ingredient and preservative, as well as a fragrance ingredient in cosmetic formulations .

Carvacrol methyl ether (Standard)	Structural Classification Natural Products other families Plants Source Classification	Reference Standards Bacterial
Carvacrol methyl ether (Standard) is the analytical standard of Carvacrol methyl ether (HY-W049970). This product is intended for research and analytical applications. Carvacrol methyl ether is a carvacrol derivative isolated from plant essential oils. Carvacrol methyl ether essentially lost its antibacterial activity, exhibiting only a weak inhibitory effect on Saccharomyces cerevisiae at the highest tested concentration of 3 g/L .

Origanum vulgare extract	Structural Classification Extract	Bacterial
Origanum vulgare extract is highly regarded for its rich content of various bioactive compounds, including carvacrol, thymol, rosmarinic acid, and other phenolic compounds, which have antioxidant, antibacterial, anti-inflammatory, and anticancer effects.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Carvacrol

Inhibitors & Agonists

Biochemical Assay Reagents

NaturalProducts

Natural
Products