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Results for "

ClC-2

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Chloride Channel (3) Potassium Channel (1) Small Interfering RNA (siRNA) (3)
By Research Areas:	Cardiovascular Disease (1) Neurological Disease (3)
Oligonucleotides:	Rat Pre-designed siRNA Sets (1) Mouse Pre-designed siRNA Sets (1) Human Pre-designed siRNA Sets (1) siRNAs (3)

Inhibitors & Agonists

Peptides

Recombinant Proteins

Antibodies

Oligonucleotides

Targets Recommended: Chloride Channel NKCC

Cat. No.	Nombre del producto	Target	Áreas de investigación	Chemical Structure

HY-P1105

GaTx2	Chloride Channel	Neurological Disease
GaTx2 is a seletive and a high affinity inhibitor of ClC-2 channels with a voltage-dependent apparent K_D of ∼20 pM. GaTx2 is a peptide toxin inhibitor from Leiurus quinquestriatus hebraeus venom. GaTx2 is useful in determining the role and the membrane localization of ClC-2 in specific cell types .

HY-106916

Unoprostone	Potassium Channel Chloride Channel	Cardiovascular Disease Neurological Disease
Unoprostone, a prostaglandin F2α analog, is a *large conductance Ca ²⁺-activated* K ⁺ (BK) channels** and ClC-2 type chloride channels activator. Unoprostone reduces oxidative stress- and light-induced retinal cell death, and phagocytotic dysfunction. Unoprostone reduces intraocular pressure and can be used for the study of glaucoma, ocular hypertension and retinitis pigmentosa ^[2].

HY-182571

AK-42	Chloride Channel	Neurological Disease
AK-42 is a selective *CLC-2* chloride channel inhibitor with human IC₅₀ of 17 nM and rat IC₅₀ of 14 nM. AK-42 binds to an extracellular vestibule above the channel pore, inhibits CLC-2 currents acutely and reversibly, including with auxiliary subunit GlialCAM coexpression. AK-42 acts as a selective tool compound for acute CLC-2 function modulation to probe CLC-2 neurophysiology. AK-42 can be used for the research of leukodystrophy and idiopathic generalized epilepsies .

HY-RS22442

Clcn2 Mouse Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Clcn2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Clcn2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

Clcn2 Mouse Pre-designed siRNA Set A Clcn2 Mouse Pre-designed siRNA Set A

HY-RS02754

CLCN2 Human Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
CLCN2 Human Pre-designed siRNA Set A contains three designed siRNAs for CLCN2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

CLCN2 Human Pre-designed siRNA Set A CLCN2 Human Pre-designed siRNA Set A

HY-RS28965

Clcn2 Rat Pre-designed siRNA Set A	Small Interfering RNA (siRNA)	Others
Clcn2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Clcn2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

Clcn2 Rat Pre-designed siRNA Set A Clcn2 Rat Pre-designed siRNA Set A

Cat. No.	Nombre del producto	Target	Research Area

HY-P1105

GaTx2	Chloride Channel	Neurological Disease
GaTx2 is a seletive and a high affinity inhibitor of ClC-2 channels with a voltage-dependent apparent K_D of ∼20 pM. GaTx2 is a peptide toxin inhibitor from Leiurus quinquestriatus hebraeus venom. GaTx2 is useful in determining the role and the membrane localization of ClC-2 in specific cell types .

Species:	Human (2) Mouse (2)
Tag:	His (2) Fc (2)
Source:	HEK293 (3) E. coli (1)

Cat. No.	Compare	Nombre del producto	Species	Source	Image

HY-P700076AF

	Animal-Free Galectin-14/LGALS14 Protein, Human (His) Placental protein 13-like/LGALS14, His; Placental Protein 13-Like; Charcot-Leyden Crystal Protein 2; ClC2; Galectin-14; Gal-14; LGALS14; PPL13	Human	E. coli
	Galectin-14/LGALS14 protein has the ability to bind β-galactoside and lactose and can serve as an effective inducer of T cell apoptosis, highlighting its key role in the regulation of immune responses. Animal-Free Galectin-14/LGALS14 Protein, Human (His) is the recombinant human-derived animal-FreeGalectin-14/LGALS14 protein, expressed by E. coli , with N-His labeled tag. This product is for cell culture use only.

HY-P70159

	Galectin-14/LGALS14 Protein, Human (HEK293, His) rHuPlacental protein 13-like/LGALS14, His; Placental Protein 13-Like; Charcot-Leyden Crystal Protein 2; ClC2; Galectin-14; Gal-14; LGALS14; PPL13	Human	HEK293
	PPL13/LGALS14 is a mammalian placenta-specific galectin with placental specificity. Many placental lectins induce apoptosis of activated T cells and other leukocytes, thereby conferring immune tolerance to the recipient. Galectin-14/LGALS14 Protein, Human (HEK293, His) is the recombinant human-derived Galectin-14/LGALS14 protein, expressed by HEK293 , with C-6*His labeled tag.

HY-P705501

	CLC2H Protein, Mouse (HEK293, Fc) C-type lectin domain family 2 member H; Clec2h; C-type lectin-related protein F (Clr-f); Clrf	Mouse	HEK293

HY-P705500

	CLC2E Protein, Mouse (HEK293, Fc) C-type lectin domain family 2 member E; Clec2e; C-type lectin-related protein A (Clr-a); Clec2e; Clra	Mouse	HEK293

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Host:	Mouse (1) Rabbit (2)
Reactivity:	Rat (2) human (1)
Application:	ICC/IF (2) IP (1) WB (3) ELISA (1)
Isotype:	IgG (2) IgG2a (1)
Conjugation:	Non-conjugated (3)
Clonality:	Monoclonal (1) Recombinant (1)
Modification:	Unmodified (2)

Cat. No.	Compare	Nombre del producto	Application	Reactivity	Image

HY-P89901

	CLC-2 Antibody (YA9245)	WB, IP, ELISA	human
	CLC-2 Antibody (YA9245) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to CLC-2.

HY-P83424

	LGALS14 Antibody (YA3169) Charcot-Leyden crystal protein 2; ClC2; Galectin-14; Gal-14	WB, ICC/IF	Rat
	LGALS14 Antibody (YA3169) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LGALS14.

HY-P83424A

	LGALS14 Antibody (YA3169)(PBS only) Charcot-Leyden crystal protein 2; ClC2; Galectin-14; Gal-14	WB, ICC/IF	Rat
	LGALS14 Antibody (YA3169) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to LGALS14.

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Products	En stock - + Add to Cart
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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / En stock - + Añadir al carrito Obtener un presupuesto

Cat. No.	Nombre del producto		Classification

HY-RS22442

Clcn2 Mouse Pre-designed siRNA Set A		siRNAs Mouse Pre-designed siRNA Sets
Clcn2 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Clcn2 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS02754

CLCN2 Human Pre-designed siRNA Set A		siRNAs Human Pre-designed siRNA Sets
CLCN2 Human Pre-designed siRNA Set A contains three designed siRNAs for CLCN2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

HY-RS28965

Clcn2 Rat Pre-designed siRNA Set A		siRNAs Rat Pre-designed siRNA Sets
Clcn2 Rat Pre-designed siRNA Set A contains three designed siRNAs for Clcn2 gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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