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GaTx2 

Cat. No.: HY-P1105
Handling Instructions

GaTx2 is a seletive and a high affinity inhibitor of ClC-2 channels with a voltage-dependent apparent KD of ∼20 pM. GaTx2 is a peptide toxin inhibitor from Leiurus quinquestriatus hebraeus venom. GaTx2 is useful in determining the role and the membrane localization of ClC-2 in specific cell types.

For research use only. We do not sell to patients.

GaTx2 Chemical Structure

GaTx2 Chemical Structure

CAS No. : 194665-85-5

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Description

GaTx2 is a seletive and a high affinity inhibitor of ClC-2 channels with a voltage-dependent apparent KD of ∼20 pM. GaTx2 is a peptide toxin inhibitor from Leiurus quinquestriatus hebraeus venom. GaTx2 is useful in determining the role and the membrane localization of ClC-2 in specific cell types[1].

IC50 & Target

Kd: 20 pM (ClC-2 channel)[1]

Molecular Weight

3192.54

Formula

C₁₂₅H₁₉₉N₃₉O₄₇S₆

CAS No.

194665-85-5

Sequence

Val-Ser-Cys-Glu-Asp-Cys-Pro-Asp-His-Cys-Ser-Thr-Gln-Lys-Ala-Arg-Ala-Lys-Cys-Asp-Asn-Asp-Lys-Cys-Val-Cys-Glu-Pro-Ile (Disulfide bridge:Cys3-Cys19;Cys6-Cys24;Cys10-Cys26)

Sequence Shortening

VSCEDCPDHCSTQKARAKCDNDKCVCEPI (Disulfide bridge:Cys3-Cys19;Cys6-Cys24;Cys10-Cys26)

SMILES

[VSCEDCPDHCSTQKARAKCDNDKCVCEPI (Disulfide bridge:Cys3-Cys19;Cys6-Cys24;Cys10-Cys26)]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

GaTx2GaTx 2GaTx-2OthersmembranelocalizationClC-2blockertoxinClC familyInhibitorinhibitorinhibit

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