15 Results for "

Claudin18.2

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "Claudin18.2" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-P99058
CAS No.: 1496553-00-4
Synonyms: IMAB362; Claudiximab; GC-182

Target:  

Inhibitory Antibodies

Research Areas:  

Cancer

Zolbetuximab (IMAB362) is a monoclonal antibody targeting Claudin-18.2. Zolbetuximab mediates specific killing of Claudin-18.2-positive cells through immune effector mechanisms. Zolbetuximab can be used for the research of gastrointestinal adenocarcinomas and pancreatic tumors .
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Cat. No.: HY-P9991
CAS No.: 2460539-61-9
Synonyms: TST001

Target:  

Gap Junction Protein

Research Areas:  

Cancer

Osemitamab is an IgG1 antibody targeting to human claudin-18.2. Osemitamab consists of human-Mus musculus monoclonal TST001 γ1-chain, disulfide with human-Mus musculus monoclonal TST001 κ-chain, dimer (ACI). Osemitamab in combination with Capecitabine (HY-B0016) and Oxaliplatin (HY-17371), can be used for G/GEJ cancer study .
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Cat. No.: HY-P990742
CAS No.: 2762499-30-7
Synonyms: TJ-CD4B; ABL111; TJ033721

Target:  

TNF Receptor Claudin

Research Areas:  

Inflammation/Immunology Cancer

Givastomig (ABL111, TJ033721) is a bispecific antibody (BsAb) inhibitor. Givastomig can specifically binds to Claudin18.2 (CLDN 18.2) on the surface of cancer cells and 4-1BB (CD137, TNFRSF9) on the surface of activated T cells and natural killer (NK) cells. Givastomig is engineered to contain a single Fc-domain mutation (asparagine to alanine) to eliminate Fc-effector function. Givastomig-bound cell lines expressing a range of CLDN18.2 levels with high affinity and induced 4-1BB activation only in the context of CLDN18.2 binding. Givastomig can be used for the study of colon carcinoma .
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Cat. No.: HY-P992412

Target:  

Claudin

Research Areas:  

Cancer

MIL93 is a humanized defucosylated IgG1 monoclonal antibody targeting Claudin18.2 (CLDN18.2) with enhanced antibody-dependent cellular cytotoxicity (ADCC) activity. MIL93 can be used for research on advanced solid tumors and gastric cancer. The recommended isotype control is human IgG1 kappa (HY-P99001) .
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Cat. No.: HY-P9991A

Target:  

Gap Junction Protein

Research Areas:  

Cancer

Osemitamab (FUT8-KO) is an anti-claudin-18.2 monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the ADCC effect of the antibody. Osemitamab in combination with Capecitabine (HY-B0016) and Oxaliplatin (HY-17371), can be used for G/GEJ cancer study .
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Cat. No.: HY-P81773
Synonyms: CLDN 18.2,Claudin 18.2

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, FC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P811601
Synonyms: CLDN 18.2,Claudin 18.2

Host:  

Rabbit

Application:  

IHC-P, ELISA, IF-Tissue, mIHC

Reactivity:  

Human, Mouse, Rat

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Cat. No.: HY-P992316

Target:  

Claudin ADC Antibodies

Research Areas:  

Cancer

ATG-022 Antibody is a humanized monoclonal antibody targeting Claudin 18.2 (CLDN 18.2). ATG-022 Antibody binds with VcMMAE (HY-15575) to form an Antibody-Drug Conjugate (ADC). ATG-022 Antibody can be used for the research of advanced/metastatic solid tumors and gastric cancer .
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Cat. No.: HY-P704502
Purity:  Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: CLDN18; Surfactant, Pulmonary Associated Protein J; Prev. SFTPJ; Claudin; Surfactant Associated Protein J; SFTA5; Claudin-18; Claudin 18; Surfactant Associated 5
Species:  
Source:  
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Cat. No.: HY-P704504
Purity:  ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: CLDN18; Surfactant, Pulmonary Associated Protein J; Prev. SFTPJ; Claudin; Surfactant Associated Protein J; SFTA5; Claudin-18; Claudin 18; Surfactant Associated 5
Species:  
Source:  
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Cat. No.: HY-P700403
Purity:  Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: CLDN18; Surfactant, Pulmonary Associated Protein J; Prev. SFTPJ; Claudin; Surfactant Associated Protein J; SFTA5; Claudin-18; Claudin 18; Surfactant Associated 5
Species:  
Source:  
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Cat. No.: HY-P700440
Purity:  Purity analysis by SDS-PAGE is not available for VLP proteins.
Synonyms: CLDN18; Surfactant, Pulmonary Associated Protein J; Prev. SFTPJ; Claudin; Surfactant Associated Protein J; SFTA5; Claudin-18; Claudin 18; Surfactant Associated 5
Species:  
Source:  
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Cat. No.: HY-P78105
Purity:  ≥ 95%, as determined by HPLC.
Synonyms: CLDN18; Surfactant, Pulmonary Associated Protein J; Prev. SFTPJ; Claudin; Surfactant Associated Protein J; SFTA5; Claudin-18; Claudin 18; Surfactant Associated 5
Species:  
Source:  
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Cat. No.: HY-P705008
Synonyms: CLDN18; Surfactant, Pulmonary Associated Protein J; Prev. SFTPJ; Claudin; Surfactant Associated Protein J; SFTA5; Claudin-18; Claudin 18; Surfactant Associated 5
Species:  
Source:  
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Cat. No.: HY-P78368
Purity:  ≥ 95%, as determined by HPLC.
Synonyms: CLDN18; Surfactant, Pulmonary Associated Protein J; Prev. SFTPJ; Claudin; Surfactant Associated Protein J; SFTA5; Claudin-18; Claudin 18; Surfactant Associated 5
Species:  
Source:  
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