9 Results for "

Complement Factor B Antibody

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "Complement Factor B Antibody" in MCE Product Catalog:

Cat. No.: HY-P810367
Synonyms: C3/C5 convertase, Complement Factor B, Glycine-rich beta glycoprotein, PBF2, Properdin Factor B

Host:  

Rabbit

Application:  

WB, ICC/IF, IHC-P

Reactivity:  

Human, Rat

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Cat. No.: HY-P99298
CAS No.: 1278466-20-8
Synonyms: RG 7417; TNX 234; Anti-CFD Recombinant Antibody

Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Lampalizumab (RG 7417) is a humanised monoclonal antibody targeting complement Factor D in the alternative complement pathway. Lampalizumab binds an exosite and sterically blocks Factor B access to the active site. Lampalizumab can be used for age-related macular degeneration (AMD) research .
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Cat. No.: HY-P990377

Target:  

Inhibitory Antibodies

Research Areas:  

Inflammation/Immunology

Anti-Complement Factor B Antibody is a CHO-expressed human antibody that targets Complement Factor B. The Anti-Complement Factor B Antibody carries a huIgG1 type heavy chain and a huκ type light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-Complement Factor B Antibody can refer to Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P990378

Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Anti-Complement Factor P/Properdin Antibody is a humanized antibody expressed in CHO, targeting Complement Factor P/Properdin. Anti-Complement Factor P/Properdin Antibody has a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 150 kDa. The isotype control for Anti-Complement Factor P/Properdin Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
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Cat. No.: HY-P990955
CAS No.: 2839652-75-2
Synonyms: ADX-097

Target:  

CD3 Complement System

Research Areas:  

Inflammation/Immunology

Ebribafusp alfa (ADX-097) comprising a humanized anti-C3d monoclonal antibody linked to two moieties of the first five consensus repeats of factor H (fH1-5). Ebribafusp alfa binds C3d and related fragments, catalyzes AP convertase dissociation, acts as a factor I co-factor for C3b cleavage, and delivers fH1-5 moieties to C3d-deposited tissues for local complement inhibition without systemic blockade. Ebribafusp alfa reduces glomerular C3 deposition, proteinuria, urine albumin-creatinine ratios, and urine soluble C5b-9 levels, preserves podocyte foot-process architecture, inhibits skin complement activation, and localizes to UVB-damaged primate skin. Ebribafusp alfa can be used for the research of membranous nephropathy, bullous pemphigoid, discoid lupus erythematosus, C3 glomerulopathy, IgA nephropathy, and lupus nephritis .
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Cat. No.: HY-P992456

Target:  

Complement System

SAR-443809 is a monoclonal antibody targeting complement factor Bb that inhibits the alternative complement pathway. SAR-443809 blocks the cleavage of C3 and factor B via selective binding to the activated form factor Bb, with a KD of 7.3 nM for human factor Bb. SAR-443809 inhibits the amplification loop of the alternative complement pathway and C3 activation, reduces C3b deposition, and blocks the activation of pathways associated with intravascular and extravascular hemolysis. SAR-443809 can be used for research on hematological and renal disorders mediated by abnormal alternative complement pathway activity .
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Cat. No.: HY-P83239
Synonyms: C3/C5 convertase; Complement Factor B; PBF2; Properdin Factor B

Host:  

Rabbit

Application:  

WB

Reactivity:  

Human

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Cat. No.: HY-P991954

Target:  

Complement System Syk

Research Areas:  

Inflammation/Immunology Cancer

GT103 is a human-derived monoclonal antibody targeting complement factor H (CFH). GT103 binds to a conformationally distinct epitope of CFH on tumor cells. GT103 activates the classical complement pathway, induces complement-dependent cytotoxicity, and triggers antibody-dependent cellular phagocytosis (ADCP) of tumor cells. GT103 increases calreticulin translocation to tumor cell plasma membranes. GT103 mediates B-cell activation via Syk kinase phosphorylation. GT103 inhibits tumor growth and metastasis in animal models. GT103 can be used for the research of non-small cell lung cancer .
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Cat. No.: HY-P83616
Synonyms: AHUS1; AMBP1; ARMD4; ARMS1; beta1H; CFH; CFHL3; Complement Factor H; isoform b; Factor H; Factor H like 1; FHL1; HF1; HF2; HUS

Host:  

Rabbit

Application:  

WB, ICC/IF

Reactivity:  

Human

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